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AANAT基因编码区多态性与家兔生长性状的关联分析

刘卜玮 王杰 陈仕毅 贾先波 赖松家

中国畜牧杂志2017,Vol.53Issue(10):25-28,4.
中国畜牧杂志2017,Vol.53Issue(10):25-28,4.DOI:10.19556/j.0258-7033.2017-10-025

AANAT基因编码区多态性与家兔生长性状的关联分析

Association Analysis between Polymorphism of Coding Sequence of AANAT Gene and Growth Traits of Rabbits

刘卜玮 1王杰 1陈仕毅 1贾先波 1赖松家1

作者信息

  • 1. 四川农业大学动物遗传育种研究所,四川成都611130
  • 折叠

摘要

Abstract

To study the association between Coding sequence(CDS)of five HT-N-acetyltransferase gene (AANAT) polymorphism and growth traits in rabbits.In the study we used direct sequencing method to detect single nucleotide polymorphism of exons of AANAT gene region with Tianfu black rabbit,IRA rabbit and New Zealand rabbit as experimental materials.There were 5 complete linkage mutation sites(C.132 T>C,C.153T>C,C.159 A>T,C.234 A>G,C.291A>G) in the CDS ofAANAT gene in the three rabbit breeds.3 genetypes(wild type:TTTTAAAAAA,heterozygous:TCTCATAGAG mutant type:CCCCTTGGGG) were formed.In New Zealand,the 56,70 and 84 days body weight of mutant type was significantly higher than those of other types rabbits and in the IRA rabbit and Tianfu black rabbit (P<0.05),70 and 84 days body weight were higher (P<0.05).The AANAT gene can be used as a candidate gene for growth traits in rabbit.

关键词

家兔/AANAT/单核苷酸基因多态性/生长性状

Key words

Rabbit/AANAT gene/SNP/Growth performance

分类

农业科技

引用本文复制引用

刘卜玮,王杰,陈仕毅,贾先波,赖松家..AANAT基因编码区多态性与家兔生长性状的关联分析[J].中国畜牧杂志,2017,53(10):25-28,4.

基金项目

四川省科技支撑计划项目(2016NYZ0046、2016NYZ0050) (2016NYZ0046、2016NYZ0050)

中国畜牧杂志

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