中国医学科学院学报2017，Vol.39Issue(4)：499-505,7.DOI:10.3881/j.issn.1000-503X.2017.04.007
性别及年龄对非酒精性脂肪肝患病情况及伴发疾病的影响
Influences of Gender and Age on the Prevalence and Complications of Nonalcoholic Fatty Liver Disease
摘要
Abstract
Objective To investigate the effects of gender and age on the prevalence and complications of nonalcoholic fatty liver disease (NAFLD).Methods A total of 8429 NAFLD patients were selected from the Health Check-up Center and Outpatient Departments of Qilu Hospital of Shandong University (Qingdao).The questionnaire-based survey,physical examinations,biochemical tests,and liver ultrasonography were performed for all cases.Patients were divided into young group (＜45 years),middle aged group (45 years ≤ age ＜ 60 years),and old group (≥ 60 years) according to age,and the clinical features and laboratory findings were analyzed.Results The proportion of male patients gradually decreased with age,while the proportion of female patients increased (P ＜ 0.01);The incidences of metabolic diseases showed significant difference among young group,middle aged group,and old group (P ＜ 0.01).Except for hyperlipidemia,the proportion of male patients with NAFLD-accompanied metabolic symdrome was significantly higher than that of female patients in all three age groups (all P ＜ 0.01).Conclusions The prevalence of NAFLD-accompanied metabolic syndrome disease is associated with age and gender.This finding is useful for the prevention and treatment of NAFLD.关键词
非酒精性脂肪肝/性别/年龄/代谢综合征Key words
nonalcoholic fatty liver disease/gender/age/metabolic syndrome分类
医药卫生引用本文复制引用
蔡美娟,孔祥楠,赵晓云..性别及年龄对非酒精性脂肪肝患病情况及伴发疾病的影响[J].中国医学科学院学报,2017,39(4):499-505,7.基金项目
山东省医药卫生科技发展计划(2014WS0130)Supported by Shandong Medical and Health Science and Technology Development Plan (2014WS0130) （2014WS0130）
