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24例严重的药品不良反应报告

高学坤 孙言才

中国医院用药评价与分析2017,Vol.17Issue(10):1411-1412,1415,3.
中国医院用药评价与分析2017,Vol.17Issue(10):1411-1412,1415,3.DOI:10.14009/j.issn.1672-2124.2017.10.040

24例严重的药品不良反应报告

24 Reports of Severe Adverse Drug Reactions

高学坤 1孙言才1

作者信息

  • 1. 安徽省肿瘤医院药剂科,安徽合肥 230031
  • 折叠

摘要

Abstract

OBJECTIVE:To investigate the incidence of severe adverse drug reactions ( ADR) in Anhui Provincial Cancer Hospital ( hereinafter referred to as "this hospital") .METHODS:367 reports of ADR during 2013-2016 were collected, analysis was conducted on 24 cases of severe ADR in terms of patients ' genders and ages , administration routes, species of drugs inducing ADR , involved organs and ( or) systems and its clinical features .RESULTS:Among the 24 reports of severe ADR , the number of male patients was slightly more than females , most aged over 60;7 cases (29.16%) were seriously ill, 17 cases (70.83%) were in hospital or prolonged hospital stays .Intravenous drip was the main administration route inducing severe ADR;the top 3 species of drugs inducing severe ADR were respectively antimicrobial drugs , antineoplastic drugs and vitamins , nutriceuticals; the severe ADR mainly involved skin and its accessories, secondly was digestive system and circulatory system .CONCLUSIONS:The severe ADR was multi-factor related, monitoring on clinical medication needs to be reinforced , related trainings on medical staff of ADR reporting are needed to ensure clinical rational medication .

关键词

药品不良反应/报告分析/合理用药/监测

Key words

Adverse drug reactions/Analysis on reports/Rational medication/Monitoring

分类

医药卫生

引用本文复制引用

高学坤,孙言才..24例严重的药品不良反应报告[J].中国医院用药评价与分析,2017,17(10):1411-1412,1415,3.

中国医院用药评价与分析

OACSTPCD

1672-2124

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