中国肿瘤生物治疗杂志2017，Vol.24Issue(10)：1045-1050,6.DOI:10.3872/j.issn.1007-385x.2017.10.001
免疫细胞的脂肪酸代谢与肿瘤免疫
Fatty acid metabolism of immune cells and tumor immunity
摘要
Abstract
Immunometabolism is a burgeoning field that aims toexplore the contribution of key metabolic pathways to immune cell development,differentiation,and function.In recent years,a substantial number of important achievements have been made in this area.Here,we focus on the latest findings related to fatty acid metabolism and immune cell functions in tumor,providing a general framework for understanding how fatty acid metabolism fuels and regulates the immune responses.By giving specific examples,this review will illustrate how the metabolites changes infatty acid metabolic pathway precisely modulate the development,differentiation and functioning of immune cellsandexplore the metabolic regulation mechanisms of immune cells in tumor micro-environment,to provide new methods and insights for studyingthe immunity mechanism in tumor.关键词
肿瘤/免疫代谢/免疫细胞/免疫应答/脂肪酸代谢Key words
tumor/immunometabolism/immune cells/immune response/fatty acid metabolism分类
医药卫生引用本文复制引用
武多娇,储以微..免疫细胞的脂肪酸代谢与肿瘤免疫[J].中国肿瘤生物治疗杂志,2017,24(10):1045-1050,6.基金项目
国家自然科学基金资助项目(No.81771672) （No.81771672）
上海市浦江人才计划资助项目(No.17PJD006):上海市卫计委资助项目(No.201740101) . Project supported by the National Nature Science Foundation of China (No.81771672),Shanghai Pujiang Program(No.17PJD006),and the Shanghai Municipal Commission of Health and Family Planning(No.201740101) （No.17PJD006）
