重庆医学2017，Vol.46Issue(31)：4336-4338,4341,4.DOI:10.3969/j.issn.1671-8348.2017.31.005
成都地区足月新生儿胎盘铅镉元素的分布特点
Distribution characteristics of placental lead and cadmium elements among full term neonates in Chengdu area
摘要
Abstract
Objective To investigate the lead and cadmium contents in different sampling sites from full term neonatal placenta and to explore the role of placental sample in the evaluation of intrauterine heavy metals exposure.Methods The placentas from 30 healthy full term neonates were collected from the West China Second Hospital of Sichuan University during May and June 2016.Each placenta fetal side was divided into the left and right parts with the umbilical vein in the umbilical cord cross-section as the 12 o'clock direction.The villus lobular tissue samples were taken from the 1/4 radius in left part (site A) and 3/4 radius in the right part (site B).The graphite furnace atomic absorption spectrometry was used to detect the lead and cadmium contents in the samples.The elements contents in the site A and B were performed the paired t-test and correlation analysis.Results The mean contents of lead and cadmium in dry weight sample at placental site A were 91.8 and 66.7μg/kg which at the site B were 88.9 and 64.8 μg/kg respectively.The lead and cadmium contents at these two sites presented the positive correlation,the coefficients were 0.98 and 0.97 respectively,whereas the difference in contents between the tissues from different placental sites had no statistical significance.Conclusion The lead and cadmium contents of villus lobular tissue in the central part of placenta fetal side (1/4-3/4 radius area) are basically consistent,which is a reliable indicator for evaluating the intrauterine heavy metals exposure.关键词
胎盘/铅/镉/石墨炉原子吸收光谱法Key words
placenta/lead/cadmium/heavy metals/graphite furnace atomic absorption spectrometry分类
医药卫生引用本文复制引用
刘丽筠,姚强,赵洪玥,朱婧,谢亮,邓莹,刘瀚旻,曾红燕,代礼..成都地区足月新生儿胎盘铅镉元素的分布特点[J].重庆医学,2017,46(31):4336-4338,4341,4.基金项目
国家自然科学基金资助项目(81673257) （81673257）
四川省科技厅项目(2013SZ0179). （2013SZ0179）
