动物营养学报2017，Vol.29Issue(11)：3844-3851,8.DOI:10.3969/j.issn.1006-267x.2017.11.002
固有免疫相关模式识别受体研究进展
Research Advancement of Innate Immunity and Pattern Recognition Receptors
摘要
Abstract
Innate immunity is the first defense against the pathogen aggression. Toll-like receptors ( TLRs) , nucleotide-binding oligomerization domain-like receptors ( NLRs) and RIG-1-like receptors ( RLRs) serve as pattern recognition receptors ( PRRs) that recognize different but overlapping microbial components, formation of the corresponding signal transduction to generate immune response. The study on innate immunity and PRRs has received grade advancement in recent years that provides a way for the treatment of immune related disea-ses. This review summarized characteristics of PRRs and the interplay across different PRR signaling pathways.关键词
固有免疫/模式识别受体/信号通路Key words
innate immunity/pattern recognition receptors/signaling pathway分类
农业科技引用本文复制引用
何邵平,贺建华,陈佳亿,陈福,欧淑琦..固有免疫相关模式识别受体研究进展[J].动物营养学报,2017,29(11):3844-3851,8.基金项目
国家自然科学基金面上项目(31672444) （31672444）
