动物营养学报2017，Vol.29Issue(11)：3987-3993,7.DOI:10.3969/j.issn.1006-267x.2017.11.019
半胱胺对宁乡猪血清生化指标和肝脏脂肪代谢的影响
Effects of Cysteamine on Serum Biochemical Indices and Liver Lipid Metabolism of Ningxiang Pigs
摘要
Abstract
This study was conducted to explore the effects of cysteamine ( CS) on serum biochemical indices and lipid metabolism in liver of Ningxiang pigs. Thirty Ningxiang barrows with an average initial weight of 43 kg were randomly allocated into 2 groups ( each group had 5 replicates with 3 pigs each) . Pigs in the control group were fed a basal diet, and in the experimental group were fed the basal diet supplemented with 80 mg/kg CS. The trial lasted for 8 weeks. The results were showed as follows:1) compared with the control group, di-etary supplementation with CS increased serum contents of glucose, low density lipoprotein and total cholesterol by 21.91% ( P<0.01) , 26.22% ( P<0.01) and 9.75% ( P<0.10) , but significantly decreased serum urea ni-trogen content by 14.14% ( P<0.05) . 2) Compared with the control group, dietary supplementation with CS significantly decreased the contents of saturated fatty acids such as C14:0, C16:0 and C20:0 by 72.09% ( P<0.01) , 13.12% ( P<0.05) and 71.13% ( P<0.01) , but increased C17:0 content by 11.77% ( P<0.10);and increased the monounsaturated fatty acid content by 40.37% (P<0.01) in which C18:1n9c content was in-creased by 55.80% ( P<0.01) , but C18:1n9t content was decreased by 85.90% ( P<0.01); while decreased the polyunsaturated fatty acid content by 7. 56% ( P<0. 05) in which C18:2n6c content was decreased by 18.56% ( P<0.01) , while contents of C22:6n3 ( DHA) and C20:3n6 were increased by 96.13% and 37.99%( P<0.01) in liver. 3) Compared with the control group, dietary supplementation with CS significantly raised the gene expression level of peroxisome proliferator-activated receptor-α ( PPARα) ( P<0.05) . It is concluded that diet supplementation with CS can increase the DHA content in liver, which may be related to the regulation of the expression of PPARαin liver tissue, and then affects the liver lipid metabolism.关键词
半胱胺/宁乡猪/血清生化指标/脂肪酸组成/脂肪代谢Key words
cysteamine/Ningxiang pig/serum biochemical indices/fatty acid composition/lipid metabolism分类
农业科技引用本文复制引用
秦龙山,邢月腾,张杨,陈宇光,舒绪刚,刘星亮,张彬,吴信..半胱胺对宁乡猪血清生化指标和肝脏脂肪代谢的影响[J].动物营养学报,2017,29(11):3987-3993,7.基金项目
湖南省重点研发计划(2015NK2004,2015JC3100) （2015NK2004,2015JC3100）
湖南省重大专项(2015NK1002) （2015NK1002）
宁乡县人民政府与湖南农业大学战略性合作项目 （）
