国际生殖健康/计划生育杂志2017，Vol.36Issue(5)：357-360,4.
以卵泡输出率为指标评估植入前遗传学诊断周期的卵巢反应性和临床结局
Prediction of PGD Outcome Based on the Follicular Output Rate
摘要
Abstract
Objective:To evaluate the follicular output rate (FORT) as a prognostic indicator of response to ovarian and the reproductive competence after PGD.Methods:A total of 158 PGD patients who underwent controlled ovarian stimulation using a long protocol were retrospectively studied.FORT was calculated as the ratio of preovulatory follicle count on the day of stimulation×100/small antral follicle count (3-10 mm in diameter) at baseline.Patients were divided into 2 groups:the low FORT group (79 women) and the high FORT group (79 women).The response of ovarian and IVF-ET pregnancy outcome were analyzed.Results:Among 158 PGD cycles,the numbers of retrieved oocytes and embryos available for transfer in the high FORT group were significantly higher than those in the low FORT group (P＜0.05).However,there were no significant differences in the 2PN fertility rate,good-quality embryos rate and blastocyst formation rate between two groups (P＞0.05).Conclusions:FORT can be used as a index to predict effectively the number of oocytes retrieved and the number of embryos for transfer in the PGD cycle,but it cannot predict the developmental potential of the embryo.关键词
植入前诊断/生殖技术,辅助/卵泡输出率/卵巢/卵泡/妊娠结局Key words
Preimplantation diagnosis/Reproductive techniques, assisted/Follicular output rate/Ovary/Ovarian follicle/Pregnancy outcome引用本文复制引用
张园,舒黎,吴畏,马翔,冒韵东,王媁,刘嘉茵..以卵泡输出率为指标评估植入前遗传学诊断周期的卵巢反应性和临床结局[J].国际生殖健康/计划生育杂志,2017,36(5):357-360,4.基金项目
卫生部行业科研专项(201402004,201302013,201002013) （201402004,201302013,201002013）
江苏省高校优势学科建设工程(JX10231802) （JX10231802）
江苏省卫生厅强卫工程项目 （）
