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抗抑郁类药物在水环境中的污染及生态毒性

雷鹏辉 杨明 湛晶 王德庆 吴明红

高校化学工程学报2017,Vol.31Issue(5):1009-1027,19.
高校化学工程学报2017,Vol.31Issue(5):1009-1027,19.DOI:10.3969/j.issn.1003-9015.2017.05.002

抗抑郁类药物在水环境中的污染及生态毒性

Pollution and Ecotoxicity of Antidepressants in Aquatic Environment

雷鹏辉 1杨明 2湛晶 3王德庆 1吴明红1

作者信息

  • 1. 上海大学 环境与化学工程学院,上海 200444
  • 2. 上海大学 射线应用研究所,上海 200444
  • 3. 上海大学 生命科学学院,上海 200444
  • 折叠

摘要

Abstract

Antidepressants are commonly prescribed psychotropic drugs. Trace levels of antidepressants and their byproducts are widely detected in wastewater and other environmental water samples with the development of chemical analysis, which is considered as emerging organic contaminants. In this review, current pollution status of antidepressants and their characteristics as well as ecotoxicity in aquatic ecosystem are discussed. Antidepressants in sewage treatment plants, sediments and aquatic organisms are reported at a range of ng.L-1 to μg.L-1 (or ng.L-1 ~μg.kg-1), and urban and hospital sewage treatment plants are considered as the major sources. Since antidepressants can accumulate in biological tissues, they are supposed to have potential chronic toxicity to organisms. Ecotoxicity data indicate that environmental antidepressants are unlikely to cause acute lethal effects on aquatic organisms. However, antidepressant exposure can affect the growth and development of aquatic animals, disrupt endocrine and reproductive functions, and alter reproductive behaviors,which has potential ecological risk and possible threatens to human health. In recent years, research on antidepressants in environment increases globally, but such research is limited in China. Therefore, it is urgent to assess the risk of antidepressant pollution in the urban water system in China.

关键词

抗抑郁药/水环境/污染特征/生态毒性

Key words

antidepressant/aquatic environment/pollution characteristics/ecotoxicity

分类

资源环境

引用本文复制引用

雷鹏辉,杨明,湛晶,王德庆,吴明红..抗抑郁类药物在水环境中的污染及生态毒性[J].高校化学工程学报,2017,31(5):1009-1027,19.

基金项目

国家自然科学基金项目(41430644, 31470554, 41673103) (41430644, 31470554, 41673103)

长江学者和创新团队发展计划(IRT13078). (IRT13078)

高校化学工程学报

OA北大核心CSCDCSTPCD

1003-9015

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