邓敏 1王大新 2谢勇 1何胜虎 1张秀菊 1朱庆勇 3陈勇 3徐日新1
作者信息
- 1. 扬州大学临床医学院苏北人民医院心内科,江苏扬州,225001
- 2. 扬州大学临床医学院生物工程医学研究室,江苏扬州,225001
- 3. 扬州大学临床医学院苏北人民医院心功能室,江苏扬州,225001
- 折叠
摘要
Abstract
Objective To study the correlation between aldosterone/renin ratio (ARR) and heart rate variability (HRV),QT interval in patients with essential hypertension.Methods A total of 179 people were divided into two groups according to median number of ARR,and 24 h Holter,24 h ambulatory blood pressure,ECG,serum potassium,serum sodium were monitored,then HRV and QT interval index were compared between the two groups.Results There were significant differences between the two groups in SDNN,SDNN index,SDANN index,RMSSD,QTc,blood potassium,sodium (P ＜ 0.05),while gender,age,diabetes,smoking,BMI,average heart rate,heart rate standard deviation showed no significant difference.At the same time,correction factors showed that ARR was still negatively correlated with SDNN,SDNN Index,SDANN Index,RMSSD,serum potassium (r =-0.444,-0.677,-0.381,-0.623,-0.432,P ＜ 0.05),andwaspositivelycorrelated with QTc,serum sodium (r =0.391,0.379,P ＜ 0.05).Multivariate logistic regression analysis showed that SDNN,SDNN Index,SDANN Index were the independent factors related to ARR (P ＜0.05).Conclusion High aldosterone is closely related to heart rate variability reduction.关键词
原发性高血压/醛固酮/心率变异性/QT间期Key words
essential hypertension/aldosterone/heart rate variability/QT interval分类
医药卫生
