摘要
Abstract
Objective To investigate the clinical effect of oral contraceptive versus placement of levonorgestrel-releasing intrauterine system (Mirena) after transcervical resection of polyp (TCRP).Methods A total of 229 patients with endometrial polyps who underwent TCRP and had pathologically confirmed endometrial polyps were enrolled,and among these patients,74 underwent the placement of Mirena during 3-5 days of menstruation and were enrolled as Mirena group,77 started to take oral contraceptive since the second day after surgery and were enrolled as contraceptive group,and 78 were not given any special treatment after surgery and were enrolled as control group.The three groups were compared in terms of menstrual blood volume,hemoglobin level,recurrence,and adverse reactions before surgery and at 3,6,and 12 months after surgery.Results The Mirena group and the contraceptive group had a significantly lower postoperative recurrence rate than the control group (x2 =8.13,15.64;P ＜ 0.05).At 3,6,and 12 months after surgery,there was a significant difference in the constituent ratio of the reduction in menstrual blood volume between the Mirena group/the contraceptive group and the control group (x2 =36.45-89.51,P ＜ 0.05).At 12 months after surgery,there was a significant difference in hemoglobin level between the three groups (F =6.62,P ＜0.05),and the Mirena group and the contraceptive group had a significantly higher hemoglobin level than the control group (q =2.644,3.46;P＜ 0.05).The Mirena group had significantly fewer adverse reactions than the contraceptive group (x2 =5.24,P＜0.05).Conclusion Both the placement of Mirena and oral contraceptive can reduce the recurrence of polyps after TCRP,and the placement of Mirena has fewer adverse effects and a higher clinical value than oral contraceptive.关键词
息肉/子宫疾病/左炔诺孕酮宫内缓释系统/避孕药,口服/曼月乐/治疗结果Key words
polyps/uterine dseases/levonorgestrel-releasing intrauterine system/contraceptives oral/Mirena/treatment outcome分类
医药卫生
