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在高反应人群中如何预防卵巢过度刺激综合征

徐蓓 靳镭

生殖医学杂志2017,Vol.26Issue(11):1071-1074,4.
生殖医学杂志2017,Vol.26Issue(11):1071-1074,4.DOI:10.3969/j.issn.1004-3845.2017.11.003

在高反应人群中如何预防卵巢过度刺激综合征

How to prevent OHSS in patients with high ovarian response?

徐蓓 1靳镭1

作者信息

  • 1. 华中科技大学同济医学院附属同济医院生殖医学中心,武汉430030
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摘要

Abstract

Ovarian hyperstimulation syndrome (OHSS) is a serious life-threatening complication associated with controlled ovarian stimulation during assisted reproductive technology (ART).Hyperresponse to gonadotrophin stimulation could possibly lead to an increase in OHSS incidence and cycle cancellation.There is currently a lack of targeted treatment for OHSS.Therefore prevention of OHSS is more important than treatment.Early recognition of risk factors for OHSS can help clinicians to adjust prevention regimens to reduce the risk of OHSS.OHSS prevention strategies include the adjustment of ovarian stimulation protocol and medication prevention.There is good evidence to support administration of GnRH antagonist protocol and using GnRH agonist to trigger oocyte maturation in women at high risk of OHSS.Additional strategies to prevent OHSS include administration of dopamine agonist,aspirin and metformin,as well as cryopreservation of whole embryos.

关键词

OHSS预防/卵巢高反应/促排方案/药物预防/体外受精-胚胎移植

Key words

OHSS prevention/Hyper-response/Medical prevention/Stimulation protocol/IVF-ET

引用本文复制引用

徐蓓,靳镭..在高反应人群中如何预防卵巢过度刺激综合征[J].生殖医学杂志,2017,26(11):1071-1074,4.

基金项目

国家自然科学基金项目(81571439) (81571439)

生殖医学杂志

OACSTPCD

1004-3845

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