生殖医学杂志2017,Vol.26Issue(11):1071-1074,4.DOI:10.3969/j.issn.1004-3845.2017.11.003
在高反应人群中如何预防卵巢过度刺激综合征
How to prevent OHSS in patients with high ovarian response?
摘要
Abstract
Ovarian hyperstimulation syndrome (OHSS) is a serious life-threatening complication associated with controlled ovarian stimulation during assisted reproductive technology (ART).Hyperresponse to gonadotrophin stimulation could possibly lead to an increase in OHSS incidence and cycle cancellation.There is currently a lack of targeted treatment for OHSS.Therefore prevention of OHSS is more important than treatment.Early recognition of risk factors for OHSS can help clinicians to adjust prevention regimens to reduce the risk of OHSS.OHSS prevention strategies include the adjustment of ovarian stimulation protocol and medication prevention.There is good evidence to support administration of GnRH antagonist protocol and using GnRH agonist to trigger oocyte maturation in women at high risk of OHSS.Additional strategies to prevent OHSS include administration of dopamine agonist,aspirin and metformin,as well as cryopreservation of whole embryos.关键词
OHSS预防/卵巢高反应/促排方案/药物预防/体外受精-胚胎移植Key words
OHSS prevention/Hyper-response/Medical prevention/Stimulation protocol/IVF-ET引用本文复制引用
徐蓓,靳镭..在高反应人群中如何预防卵巢过度刺激综合征[J].生殖医学杂志,2017,26(11):1071-1074,4.基金项目
国家自然科学基金项目(81571439) (81571439)