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医院感染中常见非发酵菌的临床分布及耐药性分析

陈斌泽 张媛媛 薛荣利 李泽慧 高志武 冯强生 周丹 张晨晨 彭俊华

西北国防医学杂志2017,Vol.38Issue(10):647-650,4.
西北国防医学杂志2017,Vol.38Issue(10):647-650,4.DOI:10.16021/j.cnki.1007-8622.2017.10.005

医院感染中常见非发酵菌的临床分布及耐药性分析

Clinical distribution and antimicrobial resistance of non-fermentative bacteria in nosocomial infection

陈斌泽 1张媛媛 1薛荣利 1李泽慧 1高志武 1冯强生 1周丹 1张晨晨 1彭俊华1

作者信息

  • 1. 解放军兰州总医院检验科,甘肃兰州 730050
  • 折叠

摘要

Abstract

Objective:To investigate the clinical distribution and antimicrobial resistance of non-fermentative bacteria causing nosocomial infection in this hospital,and to provide guidance for clinical rational use of antimicrobial agents.Methods:Specimens from patients in this hospital between January 2013 and December 2015 were cultured,identified and performed antimicrobial susceptibility testing,main non-fermentative bacteria and antimicrobial susceptibility results were analyzed statistically by WHONET 5.6 software.Results:A total of 3 533 strains of non-fermentative bacteria were isolated,in which Acinetobacter baumannii,pseudomonas aeruginosa and stenotrophomonas maltophilia accounted for 53.04%,33.29 % and 10.33 %,respectively.Non-fermentative bacteria were mainly isolated from sputum (67.39 %) and were distributed in the department of intensive care unit (ICU),emergency,respiratory medicine and neurosurgery.The susceptibility results showed that Acinetobacter baumannii and pseudomonas aeruginosa were mainly sensitive to polymyxin B and cefoperazone-sulbactam,while stenotrophomonas maltophilia were highly sensitive to minocycline and levofloxacin.Conclusion:Non-fermentative bacteria are mainly isolated from lower respiratory tract specimens in recent 3 years,and are highly resistant to multiple antimicrobial agents.Therefore,regular analysis on distribution and antimicrobial resistance of non-fermentative bacteria is helpful for the prevention and control of nosocomial infection.

关键词

医院感染/非发酵菌/临床分布/耐药性

Key words

nosocomial infection/non-fermentative bacteria/clinical distribution/drug resistance

分类

医药卫生

引用本文复制引用

陈斌泽,张媛媛,薛荣利,李泽慧,高志武,冯强生,周丹,张晨晨,彭俊华..医院感染中常见非发酵菌的临床分布及耐药性分析[J].西北国防医学杂志,2017,38(10):647-650,4.

西北国防医学杂志

1007-8622

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