西北国防医学杂志2017，Vol.38Issue(10)：651-654,4.DOI:10.16021/j.cnki.1007-8622.2017.10.006
HbA1c、Hcy及U-mAlb联合检测2型糖尿病早期肾损伤的临床意义
Clinical diagnosis value of joint detection of HbA1c, Hcy and U-mAlb in T2DM with early renal damage
王玉蓉 1戴世荣1
作者信息
- 1. 南通市第二人民医院检验科,江苏南通226002
- 折叠
摘要
Abstract
Objective:To explore the diagnosis value of joint detection of serum homocysteine (Hcy),glycosylated hemoglobin (HbA1c) and microalbuminuria (U-mAlb) in type 2 diabetes mellitus (T2DM) with early renal damage.Methods:A total of 160 patients with T2DM (84 cases of urinary protein negative group and 76 cases of urinary protein positive group) during December 2014 to March 2016 were selected as observation group,and 160 cases of healthy people taking medical examination at same period were selected as control group.The content of HbA1c,Hcy and U-mAlb were detected.At the same time the urinary protein negative group were given different detection methods,the positive rate was recorded and anaylzed.Results:The positive rate of HbA1c,Hcy and U-mAlb in observation group were higher than those in control group,the difference were statistically significant (P＜0.05).Three indicators in urinary protein positive group were significantly higher than those in urinary protein negative group,the difference were statistically significant (P ＜0.05).The total positive rate in urinary protein negative group with combined detection was 76.2％,significantly higher than the 39.3％ of detection of U-mAlb individual (P＜0.05).Conclusion:The combination of HbA1c,Hcy and U-mAlb can greatly improve the early renal damage detection rate of T2DM,worth clinical promotion.关键词
糖尿病/糖化血红蛋白/同型半胱氨酸/尿微量白蛋白/肾损伤Key words
diabetes mellitus/glycosylated hemoglobin/homocysteine/microalbuminuria/renal damage分类
医药卫生引用本文复制引用
王玉蓉,戴世荣..HbA1c、Hcy及U-mAlb联合检测2型糖尿病早期肾损伤的临床意义[J].西北国防医学杂志,2017,38(10):651-654,4.
