眼科新进展2017，Vol.37Issue(11)：1001-1004,4.DOI:10.13389/j.cnki.rao.2017.0254
大气颗粒物PM2.5附着于角膜接触镜及其对角膜接触镜透氧性及折射率的影响
Particulate matter 2.5 deposition on corneal contact lens and its effects on the oxygen permeability and refractive index of contact lenses
摘要
Abstract
Objective To observe the deposition of PM2.5 in the contact lens and its influence on the oxygen permeability and refractive index of the contact lens.Methods Atmospheric PM2.5 was collected for preparation of 1 mg · mL-1 PM2.5 suspension.Then,18 rigid gas permeable contact lenses (RGPCL) and 18 soft contact lens lenses (SCL) were grouped in control,experimental and PBS-rinse group,with 6 RGPCL and 6 SCL in each group.RGPCL and SCL in the experimental and PBS-rinse groups were incubated in 1 mg · mL-1 PM2.5 solution for 24 h,followed by PBS-rinse group were further washed for 1 h in PBS,whereas the controls were incubated in PBS for 24 h.All of them were examined with field scanning electron microscopy.Meanwhile,oxygen permeability and refractive index of contact lens were measured using the polar graphic devices and refractometry respectively.All the obtained data were quantitatively and statistically analyzed.Results After treatment in PM2.5 solution,there was a large amount of PM2.5 deposition on the RGPCL surface in the experimental group,and the amount of PM2.5 was counted (3.19 ± 1.64) · 100 μm-2,while no atmospheric particulate matter was found in the control group;following the treatment of PBS,a lot of PM2.5 attached on the surface of RGPCL remained visible,and the number of particles was (5.12 ± 1.27) · 100 μm-2.And the difference was statistically significant between the control group and PBS-rinse group (P ＜0.05).In addition,and the amount of PM2.5 attached on the surface of SCL in the exPerimental group was (2.16 ± 1.19) · 100 μm-2,while there wasn t any atmospheric particulate matter in the control group;and,after a wash of SCL in PBS,the amount of PM2.5 on SCL surface was (0.56 ±0.39) · 100 μm-2 in the PBS-rinse group,indicating a statistically difference between the control group and PBS-rinse group (P ＜0.05).Moreover,the amount of PM2.5 attachment on SCL surface in the experimental group was significantly lower than that of the control group,and the difference was statistically significant (P ＜ 0.05).After PM2.5 solution treatment,oxygen permeability of RGPCL and SCL was 100.00 ± 3.17 and 42.00 ± 2.57 respectively in the experimental group,as well as 100.00 ±2.36 and 41.00 ± 3.44 in the control group,with no statistically significant difference between the two groups (all P ＞ 0.05);while refractive index of RGPCL and SCL was 1.415 6 ±0.000 4 and 1.3737 ±0.000 7 respectively in the experimental group,as well as 1.415 3 ±0.000 4 and 1.373 7 ±0.000 l in the control group,with no statistically significant difference between the two groups either (all P ＞ 0.05).Conclusion PM2.5 can be attached to the surface of RGPCL and SCL,and PM2.5 is easier to adhere to RGPCL surface and is not easy to elute when compared with SCL,but PM2.5 deposition do not affect oxygen permeability and refractive index of contact lenses over a short span of time.关键词
大气颗粒物/PM2.5/角膜接触镜Key words
atmospheric particulate matter/PM2.5/contact lens分类
医药卫生引用本文复制引用
丁小艳,董志章,王建洲,李勇,王燕慧,许李彬,王亚虹,李娟..大气颗粒物PM2.5附着于角膜接触镜及其对角膜接触镜透氧性及折射率的影响[J].眼科新进展,2017,37(11):1001-1004,4.基金项目
国家自然科学基金资助(编号:81400424) （编号:81400424）
陕西省科学技术研究发展计划项目(编号:2014K11-03-07-04) （编号:2014K11-03-07-04）
2017年陕西省创新人才推进计划项目——青年科技新星项目(编号:2017KJXX-87)National Natural Science Foundation of Chins (No:81400424) （编号:2017KJXX-87）
Science and Technology Research and Development Project of Shaanxi Province (No:2014Kl1-03-07-04) （No:2014Kl1-03-07-04）
Youth Science and Technology Nova Project in 2017 Shaanxi Province Innovative Talent Promotion Project (No:2017KJXX-87) （No:2017KJXX-87）
