中国动脉硬化杂志2017，Vol.25Issue(10)：973-977,5.
心肌再生:心肌细胞增殖与体细胞转分化
Cardiac regeneration: cardiomyocyte proliferation and direct transdifferentiation from somatic cells
王慷慨 1肖献忠1
作者信息
- 1. 中南大学湘雅医学院病理生理学系,湖南省长沙市410078
- 折叠
摘要
Abstract
Cardiac regeneration is an important approache for treatment of myocardial infarction and recovery of heart function.The key issue to cardiac regeneration is increasing the number of cardiomyocytes.Up-to-date,increasing studies have revealed that the cell resource of regenerated cardiomyocytes mainly involves three aspects:proliferated cardiomyocytes (cardiomyocytes reentering the cell cycle,activating mitosis procedure),direct reprogramming of somatic cell (cells transdifferentiated into cardiomyocytes directly),directional differentiation based on stem cells.Although stirring progress in the above 3 aspects has been gained,there are still many problems to be solved.关键词
心肌再生/心肌细胞增殖/体细胞转分化Key words
Cardiac regeneration/Cardiomyocyte proliferation/Transdifferentiation from somatic cells分类
医药卫生引用本文复制引用
王慷慨,肖献忠..心肌再生:心肌细胞增殖与体细胞转分化[J].中国动脉硬化杂志,2017,25(10):973-977,5.
