中国动脉硬化杂志2017，Vol.25Issue(10)：1036-1040,5.
绝经后女性单核细胞/高密度脂蛋白胆固醇与冠状动脉SYNTAX评分的关系
The relationship between monocyte to high-density lipoprotein cholesterol ratio and SYNTAX score of postmenopausal women with coronary atherosclerotic heart diseases
王莹 1郑海生 1陈平 1马贵洲 1蔡志雄 1李智业 2郭海森 1王文亮1
作者信息
- 1. 汕头市中心医院心血管内科,广东省汕头市515031
- 2. 汕头市中心医院重症监护室,广东省汕头市515031
- 折叠
摘要
Abstract
Aim To investigate the relation between monocyte to high-density lipoprotein cholesterol ratio (MHR) and SYNTAX score in postmenopausal women with coronary atherosclerotic heart diseases (CAD).Methods A cohort of 180 postmenopausal women was enrolled in this study,who was diagnosed as CAD by coronary angiography.The patients were categorized in three groups based on the admission MHR level:low MHR group(MHR＜0.28,n =59),moderate MHR group(0.28≤MHR≤0.43,n=61),high MHR group(MHR＞0.43,n=60).Spearman correlation and multiple linear regression were used to describe the linear association between MHR and SYNTAX score.Results The SYNTAX scores of high MHR group (25±13) were higher than low MHR group (18±13) and moderate MHR group (19+ 12) (P=0.003).The counts of white blood cells,counts of neutrophil and serum levels of C-reactive protein in high MHR group were higher than those in low MHR group and moderate MHR group (P＜ 0.001 for all comparisons).Spearman correlation analysis showed MHR was correlated with SYNTAX score(r=0.263,P＜0.001).The result of multiple linear regression indicated that SYNTAX score was affected by MHR (F =4.777,P =0.031).Conclusion This study demonstrated that MHR of postmenopausal women with CAD was significantly positively correlated with SYNTAX score.MHR may be used to predict coronary artery lesion of postmenopausal women with CAD.关键词
绝经后女性/单核细胞/高密度脂蛋白胆固醇/SYNTAX评分/冠状动脉粥样硬化性心脏病Key words
Postmenopausal women/Monocyte to high-density lipoprotein cholesterol ratio/SYNTAX score/Coronary atherosclerotic heart disease分类
医药卫生引用本文复制引用
王莹,郑海生,陈平,马贵洲,蔡志雄,李智业,郭海森,王文亮..绝经后女性单核细胞/高密度脂蛋白胆固醇与冠状动脉SYNTAX评分的关系[J].中国动脉硬化杂志,2017,25(10):1036-1040,5.
