中国动脉硬化杂志2017，Vol.25Issue(10)：1047-1053,7.
2001～2011年中国中西部城市地区急性心肌梗死患者住院期间他汀应用变化趋势及影响因素——China PEACE回顾性急性心肌梗死研究
Statin therapy in patients hospitalized with acute myocardial infarction in central-western urban China from 2001 to 2011 : the China PEACE-retrospective acute myocardial infarction study
摘要
Abstract
Aim To illustrate patterns of statin therapy in patients with Acute Myocardial Infarction (AMI) in central-western urban China from 2001 to 2011,and identify factors affecting the use of statins.Methods A two-stage random sampling design was used to create a representative sample of patients who were admitted to hospital for AMI in central-western urban China in 2001,2006 and 2011.In the first phase,simple random-sampling procedure was used to identify participating hospitals.In the second phase,patients were selected from each sampled hospital in above 3 years through a systematic sampling approach.Medical records were centrally abstracted to get patients' information.The findings were weighted for each year to represent the overall situation.Binary logistic regression analysis was used to identify factors related to the use of in-hospital statins.Results 31 randomly sampled urban hospitals in central-western China participated in the study,and 3 354 AMI admissions were included in analysis.There has been a significant increase in the use of statin therapy,the proportion of which was 19.7％ in 2001,79％ in 2006,and 91.1％ in 2011.Overall,statin use significantly increased among all low density lipoprotein-cholesterol (LDLC) groups during 10 years.Lovastatin was the most common stain in 2001 and it turned to be atorvastatin in 2011.Logistic regression analysis showed that patients who smoke (OR=1.36;95％ CI 1.07～1.73,P=0.011) were more likely to be treated with statin therapy.Conclusion During the past decade,the use of statin therapy has dramatically increased in central-western China.However,a lot still needs to be done to optimize the use of statin therapy among AMI patients.关键词
急性心肌梗死/他汀/血脂/变化趋势Key words
Acute myocardial infarction/Statin/Lipid/Temporal trend分类
医药卫生引用本文复制引用
霍西茜,张丽华,胡爽,吴超群,张丹薇,李静,李希,郑昕,蒋立新..2001～2011年中国中西部城市地区急性心肌梗死患者住院期间他汀应用变化趋势及影响因素——China PEACE回顾性急性心肌梗死研究[J].中国动脉硬化杂志,2017,25(10):1047-1053,7.基金项目
卫生公益性行业科研专项(201202025、201502009) （201202025、201502009）
国家科技支撑计划项目(2013BAI09B01、2015BAI12B01和2015BAI12B02) （2013BAI09B01、2015BAI12B01和2015BAI12B02）
