中国畜牧兽医2017，Vol.44Issue(9)：2613-2620,8.DOI:10.16431/j.cnki.1671-7236.2017.09.011
外源褪黑素处理方式对荷斯坦奶牛体内褪黑素富集与代谢的影响
Effects of Different Melatonin Injection Ways on the Enrichment and Metabolism of Blood Melatonin in Holstein Cows
摘要
Abstract
Ahstract:In order to exploring the change pattern of melatonin in blood under the normal conditions of the multiparous Holstein cows within 24 h,the change of melatonin in blood of Holstein cows after the intravenous injection,subcutaneous implantation in neck,neck subcutaneous injection and drench were studied and the melatonin secretion rule and its metabolic rate were analyzed.The results showed that melatonin secretion changes obviously in the blood within 24 h,the concentration peak appeared at 04:00 (8.30 ng/mL),lowest at 16:00 (2.08 ng/mL).After subcutaneous implantation and drench,the concentration of melatonin in the blood rose relatively flat compared to other groups.Subcutaneous injection of 46.4,4.64 and 0.464 mg melatonin,the concentration in the blood rose rapidly,the peak appeared at 1 h after the injection,which were 561.94,487.03,92.89 ng/mL,respectively,extremely significantly higher than pre-injection (P＜0.01).Intravenous injection of 46.4,4.64 and 0.464 mg melatonin,the concentration in the blood also rose rapidly,the peak appeared at 0.5 h after the injection,which were 767.68,639.19,110.56 ng/mL,respectively,extremely higher than pre-injection (P ＜ 0.01).This study proved that the secretion of melatonin in the Holstein cows had obvious circadian rhythm,intravenous or subcutaneous injection of melatonin could improve the concentration of melatonin rapidly and there was a high correlation between the melatonin metabolic rate and the melatonin concentration in the blood,with the increase of the concentration of melatonin,the metabolism velocity was accelerated obviously.关键词
荷斯坦奶牛/褪黑素/埋植/皮下/静脉注射/代谢速度Key words
Holstein cows/melatonin/implantation/subcutaneous/intravenous injection/metabolic rate分类
农业科技引用本文复制引用
杨明辉,路永强,何长久,杨利国,刘国世,史建民,陶景丽,吴昊,柴孟龙,王静,任康,徐志远,姬鹏云..外源褪黑素处理方式对荷斯坦奶牛体内褪黑素富集与代谢的影响[J].中国畜牧兽医,2017,44(9):2613-2620,8.基金项目
北京市奶牛产业创新团队(BAIC06-2016) （BAIC06-2016）
国家自然科学基金项目(31372306) （31372306）
