磁共振成像2017，Vol.8Issue(11)：834-838,5.DOI:10.12015/issn.1674-8034.2017.11.007
钆塞酸二钠增强MRI对肝功能评估价值的血清学对照研究
The clinical study on the Gd-EOB-DTPA-enhanced MR imaging for analysis of liver function and comparison with serologic results
摘要
Abstract
Objective: To investigate the clinical significance of Gd-EOB-DTPA to predict and evaluate the liver function. Materials and Methods: Gd-EOB-DTPA-enhanced MR images of 98 patients were conducted on a 3.0 Tesla MRI. The values of relative enhancement ratio (rER) and Child-Pugh scores were calculated. Serologic testing was obtained within 7 days before and after MRI. The comparison between different Child-Pugh groups was accomplished by One-Way ANOVA. Spearman rank correlation was applied to analyze the relationship between the rER values and serologic results. Results:The results showed statistical differences among rER values of different Child-Pugh groups and normal group (P<0.05). The mean values are respectively 2.281±0.275, 2.092±0.474,1.824±0.246, 1.711±0.433. Comparative analysis between every two groups was applied and the results showed that normal and Child-Pugh B, normal and Child-Pugh C, Child-Pugh A and Child-Pugh B indicated statistical significance. The linear regression analysis showed that P value between rERs and values of TBIL, ALT, AST, PT, PTA, PA, ChE were less than 0.05, which was significant statistically. Conclusions: The rER values of EOBMRI could be used to evaluate liver function and to identify mild, moderate liver damage significantly. It got the most intimate relation with prothrombin activity and prealbumin.关键词
造影剂/肝功能/血清学/磁共振成像Key words
Contrast media/Liver function/Serology/Magnetic resonance imaging分类
医药卫生引用本文复制引用
朱望舒,石思雅,杨绮华,宋超,李勇..钆塞酸二钠增强MRI对肝功能评估价值的血清学对照研究[J].磁共振成像,2017,8(11):834-838,5.基金项目
广东省自然科学基金(编号:S2013010016131)Supported by the Natural Science Foundation of Guangdong Province, China (No. S2013010016131). （编号:S2013010016131）
