南方医科大学学报2017，Vol.37Issue(9)：1171-1177,7.DOI:10.3969/j.issn.1673-4254.2017.09.05
电针对食蟹猴单侧前交叉韧带损伤后本体感觉的影响
Effect of electroacupuncture on proprioception in cynomolgus monkeys after unilateral anterior cruciate ligament injury
摘要
Abstract
Objective To study the effect of electroacupuncture on proprioception in cynomolgus monkeys after unilateral anterior cruciate ligament (ACL) injury.Methods Twenty-seven cynomolgus monkeys were randomized equally into 3 groups,namely unilateral ACL injury with electroacupuncture group,unilateral ACL injury model group and blank control group.One week after modeling,the monkeys in electroacupuncture group were treated daily for 12 weeks with electroacupuncture at the acupoints Wei Yang,Yin Gu,Xi Yangguan and Qu Quan.At 4,8,and 12 weeks during the treatment,the changes in the somatosensory evoked potentials (SEPs) and motor nerve conduction velocity (MCV) of the nerves of the ACL were examined with neural electrophysiological method;the changes in the morphology and the total and variable number of the proprioceptors in the ACL were observed with gold chloride staining.Results In the mokeys in the model group,the incubation period of the SEPs and MCV on the injured side of the knee were significantly extended and the amplitudes were decreased with the passage of time (P＜0.05).Intervention with electroacupuncture significantly reduced the incubation period and increased the amplitudes of the SEPs and MCV (P＜0.05).The total number of the proprioceptors in the ACL was significantly decreased and the variable number of the proprioceptors in ACL was increased with time in the monkeys in the model group (P＜0.05);electroacupuncture intervention obviously slowed the reduction rate of total number of the proprioceptors (P＜0.05) but without affecting the variable number of the proprioceptors (P＞0.05).Conclusion ACL injury causes attenuation of the proprioception on the injury side,and electroacupuncture intervention can produce a positive effect on the proprioception in cynomolgus monkeys.关键词
前交叉韧带/本体感觉/本体感受器/电针Key words
anterior cruciate ligament/proprioception/proprioceptor/electroacupuncture引用本文复制引用
张磊,李义凯,祁冀,张少群,平瑞月,周鑫,喻林,刘锐锋,扶世杰..电针对食蟹猴单侧前交叉韧带损伤后本体感觉的影响[J].南方医科大学学报,2017,37(9):1171-1177,7.基金项目
国家自然科学基金(81674095) （81674095）
四川省教育厅科研项目(17ZB0472) （17ZB0472）
泸州市科技局科技计划项目(2016-176-13)Supported by National Natural Science Foundation of China (81674095). （2016-176-13）
