南方医科大学学报2017，Vol.37Issue(9)：1222-1227,6.DOI:10.3969/j.issn.1673-4254.2017.09.14
640层3D-CTA联合3D打印脑动脉瘤成像的临床价值
Value of 640-slice 3D CT angiography plus 3D printing for improving surgeries for intracranial aneurysms
摘要
Abstract
Objective To evaluate the value of 640-slice 3D CT angiography (3D-CTA) plus 3D printing for improving the outcomes of surgeries for intracranial aneurysms.Methods Sixty patients with intracranial aneurysm were randomly divided into trial group (n=30) and control group (n=30).The control group received routine surgery,and the simulation models of the intracranial aneurysm in trial group was printed using a 3D printer using the imaging data from 3D-CTA.Using the simulation model,the surgery was designed and planned before operation (including surgical approaches and placement of clips) and simulation surgery was also conducted.The coincidence rates between preoperative and intraoperative findings of the intracranial aneurysms on 3D-CTA were compared.CT scan was performed at 1 and 3 days after the operation to detect potential cerebral infarction or bleeding associated with the operation;CTA was performed both at the same time and at 3-6 months after the operation to detect stenosis,occlusion and aneurysm clipping.The patients were followed up for 3-6 months to assess the outcomes using Glasgow Outcome Scale (GOS).Results The preoperative 3D-CTA findings were basically consistent with the intraoperative findings in all the 60 patients.Nine patients in the control group and 2 patients in the trial group had short-term adverse operation events;11 patients in control group and 4 patients in trial group had long-term adverse events;18 patients in control group and 25 patients in trial group had good neurologic function.The incidences of short-term and long-term adverse events associated with the operation was significantly lower in the trial group than in the control group (xx=5.364,P=0.021;x2=4.841,P=0.028),and the outcomes were significantly better in the trial group than in the control group (x2=4.633,P=0.031).Conclusion The simulation model of intracranial aneurysm is helpful to improve the quality of surgery and patients outcomes.关键词
X线计算机/3D-CTA/3D打印/颅内动脉瘤/模拟手术Key words
X-ray computed/3D-CTA/intracranial aneurysms/3D printing/surgical simulation引用本文复制引用
周路球,娄明武,陈国昌,纠智松,申云霞,鲁琳..640层3D-CTA联合3D打印脑动脉瘤成像的临床价值[J].南方医科大学学报,2017,37(9):1222-1227,6.基金项目
深圳市科技创新委员会基金(JCY20140411150717070) （JCY20140411150717070）
