南方医科大学学报2017，Vol.37Issue(9)：1242-1247,6.DOI:10.3969/j.issn.1673-4254.2017.09.17
正常成人脑部皮层下灰质结构的3D pc-ASL灌注成像的可重复性
Test-retest reliability of 3D spiral fast-spin-echo pseudo-continuous arterial spin labeling for cerebral perfusion imaging of subcortical gray matter in healthy adults
刘梦琦 1陈志晔 2马林1
作者信息
- 1. 中国人民解放军总医院海南分院放射科,海南三亚572013
- 2. 中国人民解放军总医院放射科,北京100853
- 折叠
摘要
Abstract
Objective To evaluate the test-retest reliability of 3D spiral fast-spin-echo (FSE) pseudo-continuous arterial spin labeling (3D pc-ASL) for cerebral perfusion imaging of the subcortical gray matter in healthy adults in resting state.Methods 3D spiral FSE ASL and 3D T1-weighted fast spoiled gradient recalled echo (3D T1-FSPGR) sequences were used for cerebral perfusion imaging in 8 healthy adult subjects,and a repeat imaging examination was performed after one week.The subcortical gray matter structures including the putamen,globus pallidus,caudate nucleus,thalamus,amygdala and hippocampus were segmented on the brain structural 3D images to generate the cerebral blood flow (CBF) map.The CBF value was extracted based on the segmented images and the CBF maps.The reliability and reproducibility of the measurements were evaluated using the intradass correlation coefficient (ICC) and Bland-Altman plot.Results The mean ICC value of the subcortical gray matter structures was 0.88±0.04 (range,0.80-0.93).The Bland-Altman plot analysis demonstrated that the differences between the two measurements at all the points corresponding to the subcortical gray matter structures were within 95％ CI of the limits of agreement.Conclusion 3D spiral FSE pseudo-continuous ASL is a reliable method for assessing the perfusion of the cerebral subcortical gray matter structures.关键词
动脉自旋标记/脑/组内相关系数/磁共振成像/皮层下灰质Key words
arterial spin labeling/brain/intraclass correlation/magnetic resonance imaging/subcortical gray matter引用本文复制引用
刘梦琦,陈志晔,马林..正常成人脑部皮层下灰质结构的3D pc-ASL灌注成像的可重复性[J].南方医科大学学报,2017,37(9):1242-1247,6.
