南方医科大学学报2017，Vol.37Issue(9)：1248-1251,4.DOI:10.3969/j.issn.1673-4254.2017.09.18
基于MRI图像的眼眶脂肪体积定量测定方法
A novel method for quantitative measurement of orbital fat volume based on magnetic resonance images
摘要
Abstract
Objective To establish a new method for rapid and quantitative measurement of orbital fat volume based on magnetic resonance imaging (MRI) data.Methods We collected MRI data from normalized mold and patients with the diagnosis of thyroid-associated ophthalmopathy (TAO).The cross-sectional areas of the orbital fat on each MR image slice were measured to calculate the fat volume on each slice and then the total orbital fat volume.We recorded the time for completing the measurement and assessed the precision,reliability,repeatability and interoperator variations of the results.Results This MRI data-based method allowed precise measurement of the orbital fat volumes with an absolute value of the mean percentage difference ＜1％.This method was fast and the results showed a good repeatability (with CVs ＜1％),a high reliability (ICC=0.996,95％ CI:0.985-0.999) and a high interoperator concordance (95％ CI of the Bland-Altman:-0.54-0.90).Conclusion The novel method we established for orbital fat volume measurement is rapid,accurate,reliable and reproducible with a low learning cost for clinical use.关键词
眼眶脂肪体积/甲状腺相关性眼病/MRI/定量测量Key words
orbital fat volumes/thyroid-associated ophthalmopathy/magnetic resonance imaging/quantitative measurement引用本文复制引用
蔡秋月,陈智毅,蒋薇,罗耀升,李章芳,胡世弟,沈洁..基于MRI图像的眼眶脂肪体积定量测定方法[J].南方医科大学学报,2017,37(9):1248-1251,4.基金项目
广东省高水平大学建设项目临床研究基金(LC2016PY046) （LC2016PY046）
广东省基础研究及应用研究重大项目(2016KZDXM019) （2016KZDXM019）
