南方医科大学学报2017，Vol.37Issue(9)：1256-1260,5.DOI:10.3969/j.issn.1673-4254.2017.09.20
牙周干预治疗降低口腔颌面部肿瘤患者术后的下呼吸道感染
Prior periodontal intervention lowers incidence of lower respiratory infection in patients receiving oral and maxillofacial tumor surgery
摘要
Abstract
Objective To investigate whether periodontal infection is a risk factor for lower respiratory infection patients receiving oral and maxillofacial tumor surgery.Methods Patients undergoing oral and maxillofacial surgery for tumors with concurrent periodontal disease between January,2012 and December,2016 were randomized into periodontal intervention group and control group (treated with gargle solution containing chlorhexidine gluconate).The one-time periodontal intervention was completed within 24 h in the intervention group and two-week mouthwash was prescribed in the control group before oral and maxillofacial tumor surgery.Five periodontal indexes were examined at baseline and at 6 weeks after the treatment.The clinical symptoms and incidence of lower respiratory infections were compared between the two groups at 6 weeks.Results The PLI,BOP,PPD,and CAL were significantly lower and GR was higher in the intervention group than in the control group (P＜0.01).The periodontal status was sigrtificantly improved in the intervention group.The incidence of lower respiratory infection was significantly lower in the intervention group than in the control group (2.22％ vs 7.11％,P＜0.01).The incidences of cough and expectoration in the intervention group were significantly lower than those in control group (P＜ 0.01).Conclusions Periodontal infection is one of the risk factors for lower respiratory infection after oral and maxillofacial tumor surgery.The periodontal status can be effectively controlled and improved by periodontal intervention.Compared with mouthwash,periodontal intervention can significantly reduce the incidences of cough and expectoration and lower the incidence of lower respiratory infections.关键词
牙周感染/颌面部肿瘤/牙周干预治疗/下呼吸道感染Key words
periodontal infection/oral and maxillofacial tumor/periodontal intervention/lower respiratory infection引用本文复制引用
游杰,杨雅洁,刘丽燕,胡琛..牙周干预治疗降低口腔颌面部肿瘤患者术后的下呼吸道感染[J].南方医科大学学报,2017,37(9):1256-1260,5.基金项目
国家自然科学基金(81701026) （81701026）
广东省医学科学技术研究基金(A2017539)Supported by National Natural Science Foundation of China (81701026). （A2017539）
