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口腔扁平苔藓患者幽门螺杆菌感染状况分析

姚小武 卢子正 刘少飞

口腔疾病防治2017,Vol.25Issue(11):729-732,4.
口腔疾病防治2017,Vol.25Issue(11):729-732,4.DOI:10.12016/j.issn.2096-1456.2017.11.010

口腔扁平苔藓患者幽门螺杆菌感染状况分析

Analysis of Helicobacter pylori infection in patients with oral lichen planus

姚小武 1卢子正 1刘少飞1

作者信息

  • 1. 汕头大学医学院第二附属医院口腔科,广东汕头 515041
  • 折叠

摘要

Abstract

Objective To explore the correlation between oral mucosal lichen planus and Helicobacter pylori infec-tion by analyzing the infection status of Helicobacter pylori in patients with oral mucosal lichen planus. Methods 14C-urea breath test was done in 69 patients with oral lichen planus and 28 patients with chronic inflammation of oral muco-sa. Detection of serum anti Helicobacter pylori antibody was done in 32 patients (23 with oral lichen planus and 9 with chronic inflammation of oral mucosa) at the same time. Results The positive rate of 14C-urea breath test was 68.12%in patients with oral lichen planus and 46.43%in chronic inflammation of oral mucosa. There was significant difference between the 2 groups (x2=3.970, P=0.046). The positive rate of anti Helicobacter pylori antibody was 52.17% in pa-tients with oral lichen planus and 22.22% in chronic inflammation of oral mucosa, and there was no significant differ-ence between the 2 groups (x2=2.358, P=0.125). Conclusion The prevalence of Helicobacter pylori infection in pa-tients with oral lichen planus is higher, and there is a relevance between oral lichen planus and Helicobacter pylori infec-tion.

关键词

口腔扁平苔藓/幽门螺杆菌/14C-尿素呼气试验/抗Hp抗体/相关性

Key words

Oral lichen planus/Helicobacter pylori/14C-urea breath test/Anti Hp antibody/Relevance

分类

医药卫生

引用本文复制引用

姚小武,卢子正,刘少飞..口腔扁平苔藓患者幽门螺杆菌感染状况分析[J].口腔疾病防治,2017,25(11):729-732,4.

基金项目

广东省科技计划项目(2013B021800260) (2013B021800260)

口腔疾病防治

OACSTPCD

1006-5245

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