国际医药卫生导报2017，Vol.23Issue(22)：3495-3497,3508,4.DOI:10.3760/cma.j.issn.1007-1245.2017.22.005
来曲唑在体外受精-胚胎移植卵巢储备低下患者中的应用研究
The influence of letrozole administration upon the outcome of in vitro fertilization-embryo transfer in patients with poor ovarian reserve
摘要
Abstract
Objective To investigate the influence of letrozole (LE) administration upon the outcome of in vitro fertilization-embryo transfer (IVF-ET) with CC/Gn protocol in patients with poor ovarian reserve.Methods 273 patients with poor ovarian reserve undergoing 323 IVF-ET cycles with CC/Gn protocol were analyzed retrospectively.According to administration of LE,they were divided into Group LE and Group non-LE.Results The level of hormone and count of follicles on the day of starting,the count of oocytes retrieved,the count/rate of normal fertility,available embryo,and high-quality embryo were not significantly different between the two groups (P＞0.05).E2,P on the day of HCG,the days and total amount of Gn in Group non-LE were significantly higher than those in Group LE (P＜0.05).There were no statistically significant differences between the two groups in the total pregnancy rate,delivery and continued pregnancy rate,abortion rate,ectopic pregnancy rate (P＞0.05),but chemical pregnancy rate in Group LE was significantly higher than that in Group non-LE (P＜0.05).Conclusion The administration of LE in patients with poor ovarian reserve of IVF-ET with CC/Gn protocol can contribute to reduce the total amount and days of Gn and improve the efficiency of Gn,with higher chemical pregnancy rate.关键词
体外受精-胚胎移植/来曲唑/卵巢储备低下Key words
In vitro fertilization-embryo transfer/Letrozole/Poor ovarian reserve引用本文复制引用
陈希曦,黎淑贞,黎平..来曲唑在体外受精-胚胎移植卵巢储备低下患者中的应用研究[J].国际医药卫生导报,2017,23(22):3495-3497,3508,4.
