摘要
Abstract
Objective To investigate the relationship between atypical antipsychotics and cerebrovascular accidents in patients with Alzheimer's disease.Methods A total of 176 cases of Alzheimer's disease in our hospital were given atypical antipsychotic treatment,the treatment period was 3 months,compared the levels of risk factors of cerebrovascular accidents [mean arterial pressure,blood glucose,triglyceride (TG)] before and after treatment,and evaluated the relationship between the two.Results The incidence of cerebrovascular accidents 1 month after treatment was significantly lower than that 3 months after treatment (17.6％ vs.31.3％,P＜0.05);before treatment,1 month after treatment,3 months after treatment,mean arterial pressure showed a gradually decreasing trend,fasting blood glucose and TG showed a gradually increasing trend,the three indexes were respectively significantly different (P＜0.05).Conclusion Atypical antipsychotics can cause low blood pressure,hyperglycemia,and high TG in Alzheimer's patients,which can lead to cerebrovascular accidents.关键词
非典型抗精神病药物/阿尔茨海默病/脑血管意外/关系研究Key words
Atypical antipsychotics/Alzheimer's disease/Cerebrovascular accident/Relationship study
