河北医学2017，Vol.23Issue(11)：1779-1783,5.DOI:10.3969/j.issn.1006-6233.2017.11.006
食管癌CD34 VEGF表达与CT强化幅度的关系
The Relationship between the Expression of CD34 and VEGF and the Magnitude of CT Enhancement in Esophageal Carcinoma
摘要
Abstract
Objective:To analyze the relationship between the expression of CD34 and VEGF and the enhancement of CT in esophageal carcinoma. Methods:The organization of esophageal mucosa in 40 cases of esophageal carcinoma and 20 cases of healthy people were collected from our hospital, the expression of CD34 and VEGF protein were detected by immunohistochemistry in tissue, and the MVD was counted, measured CT scan cancer CT enhancement value, will be between the indexes and clinical stages of the tumor and its rela-tion to statistics analysis. Result:Compared with healthy control group, the positive expression rate of CD34 and VEGF in esophageal carcinoma group were higher (P<0.05), and they were positively correlated in e-sophageal cancer tissues (r=0.451, P<0.05); The expression of VEGF and MDV in esophageal carcinoma were correlated with the degree of cell differentiation, depth of invasion, lymph node metastasis and clinical TNM stage ( P<0.05);the expression of VEGF in esophageal cancer tissues ( r=0.434, P<0.05) and MVD (r=0.463, P<0.05) with spiral CT enhancement was positively correlated, the differences were statistically significant. Conclusion:CD34 and VEGF were highly expressed in esophageal cancer, and CD34, VEGF and CT enhancement in esophageal carcinoma are related, are important indicators of combined detection can be used as the invasion and metastasis of esophageal carcinoma and prognosis judgement.关键词
食管癌/CD34/VEGF/MVD/CT强化幅度Key words
Esophageal carcinoma/CD34/VEGF/MVD/CT enhancement引用本文复制引用
邢媛媛,赵佳佳,曹宏伟,王胜林,吴薇娜,李春晖..食管癌CD34 VEGF表达与CT强化幅度的关系[J].河北医学,2017,23(11):1779-1783,5.基金项目
河北省科技指令性课题,(编号:12276104D-20) （编号:12276104D-20）
