河北医学2017，Vol.23Issue(11)：1805-1810,6.DOI:10.3969/j.issn.1006-6233.2017.11.013
280例cT1aN0 M0肺腺癌淋巴结转移影响因素的回顾性分析
Retrospective Analysis of Influencing Factors of Lymph Node Metastasis in 280 Cases of cT1aN0M0 Lung Adenocarcinoma
张书勤 1魏柏 1丰小敏 1夏佩 1马薇1
作者信息
- 1. 华中科技大学同济医学院附属梨园医院肿瘤科,湖北 武汉 430077
- 折叠
摘要
Abstract
Objective:To explore the risk factors of lymph node metastasis in cT1aN0 M0 lung adenocar-cinoma. Methods:The clinical data of 280 cases of cT1aN0 M0 lung adenocarcinoma patients admitted between January 2013 and December 2015 in our hospital were selected, and the lymph node metastasis and clinical factors were retrospectively analyzed. The pathological characteristics and clinical data of the patients, single factor and multiple factors analysis were done to explore the influence factors of lymph node metastasis of cT1aN0 M0 lung adenocarcinoma. Results:After all the 280 patients with cT1aN0 M0 lung adenocarcinoma un-derwent thin slice CT scan, 108 patients ( 38. 6%) were found to have pure glass opacity in CT imaging. Ground glass opacity combined with solid components (<5mm) were found in 117 cases (41.8%). Ground glass opacity combined with solid nodules ( solid component diameter <5mm ) were found in 12 cases ( 4. 3%), pure solid nodules (solid component diameter≥5mm) were found in 43 cases (15.4%). Patients with lymph node metastasis were 28 (10%), of which 16 patients (5.7%) with N1 lymph node metastasis and 12 patients (4.3%) with N2 lymph node metastasis. In this study, all of the patients with a diameter of less than 5 mm in diameter or with pure ground glass opacity, no lymph node metastasis after surgery were found, P<0. 05, the difference was significant. Conclusion: For cT1aN0 M0 lung adenocarcinoma patients, if the imaging performance were pure grinding glass or solid components of the diameter is less than 5 mm, there is usually no lymph node metastasis occurred. In patients with tumor diameter greater than 1cm, mixed nodules and solid nodules and μg/L CEA>5 were important prognostic factors for lymph node metastasis. Analysis of the maxi-mum standard uptake value in patients with PET-CT showed that patients were more likely to have lymph node metastasis when the maximum standard uptake value was greater than 5( P<0.05) .关键词
肺腺癌/淋巴结/淋巴结转移/临床预测因素/临床分期Key words
Lung cancer/Lymph node/Lymph node metastasis/Clinical predictors/Clinical stage引用本文复制引用
张书勤,魏柏,丰小敏,夏佩,马薇..280例cT1aN0 M0肺腺癌淋巴结转移影响因素的回顾性分析[J].河北医学,2017,23(11):1805-1810,6.
