解放军医学院学报2017，Vol.38Issue(9)：824-826,849,4.DOI:10.3969/j.issn.2095-5227.2017.09.005
应用两种不同核黄素溶液的离子导入交联治疗进展期圆锥角膜后基质分界线深度比较
Comparison of depth of demarcation line in iontophoresis-assisted corneal crosslinking using different riboflavin solution for progressive keratoconus
摘要
Abstract
Objective To compare the depth of demarcation line in iontophoresis-assisted corneal crosslinking (I-CXL) using 0.1％ riboflavin-distilled water solution versus in I-CXL using 0.1％ riboflavin-sodium lactate Ringer's solution for progressive keratoconus.Methods From January to July in 2013,clinical data about 11 patients (16 eyes) treated with I-CXL using 0.1％ riboflavin-sodium lactate Ringer's solution were collected;and from August 2013 to November 2015,clinical data about 62 patients (78 eyes) treated with I-CXL using 0.1％ riboflavin-distilled water solution were collected.Anterior segment OCT was used to examine the depth of demarcation line and they were compared between two groups at 1 month after treatment.Results The depth of demarcation line was (268.25 ± 18.06) μ m in patients treated by I-CXL using 0.1％ riboflavin-sodium lactate Ringer's solution,and it was (298.95 ± 51.97) μ m in patients treated by I-CXL using 0.1％ riboflavin-distilled water with statistically significant difference between two groups (t=3.594,P=0.001).The incidences of demarcation line in the two groups were 56.3％ and 83.1％ respectively,and the difference was statistically significant (x 2=5.514,P=0.019).Conclusion The efficacy of I-CXL using 0.1％ riboflavindistilled water solution is better than that of I-CXL using 0.1％ riboflavin-sodium lactate Ringer's solution for progressive keratoconus.关键词
进展期圆锥角膜/角膜交联/离子导入/核黄素Key words
progressive keratoconus/corneal crosslinking/iontophoresis/riboflavin分类
医药卫生引用本文复制引用
贾洪真,庞旭,李刚,李娜,隋艳来,樊郑军,彭秀军..应用两种不同核黄素溶液的离子导入交联治疗进展期圆锥角膜后基质分界线深度比较[J].解放军医学院学报,2017,38(9):824-826,849,4.基金项目
北京市科技计划资助项目(Z151100004015217)Supported by the Science and Technology Program of Beijing(Z151100004015217) （Z151100004015217）
