检验医学与临床2017，Vol.14Issue(22)：3316-3317,3320,3.DOI:10.3969/j.issn.1672-9455.2017.22.014
妊娠高血压孕妇妊娠中期的血脂及血脂蛋白研究
Study on blood lipid and lipoprotein during mid trimester of pregnancy in women with pregnancy induced hypertension
摘要
Abstract
Objective To investigate the characteristics of blood lipid and lipoprotein during the mid trimester of pregnancy in pregnant women with pregnancy induced hypertension .Methods The retrospective analysis was performed on 4762 pregnant women in this hospital from January 2009 to January 2017 ,including 286 cases of hypertensive disorders in pregnancy (disease group)and 4476 cases of normal blood pressure(control group) .the body mass index(BMI) ,triglyceride(TG) ,low density lipopro-tein cholesterol(LDL-C) ,high density lipoprotein cholesterol(HDL-C) ,total cholesterol(TC) ,apolipoprotein(ApoA1 ,ApoB ,ApoE) and lipoprotein[Lp(a)] during 18-24 gestational weeks were observed in the two groups .Results BMI in the disease group was higher than that in the control group ,the difference was statistically significant (P<0 .05) .TG ,LDL-C and TC in the disease group were higher than those in the control group ,while HDL-C was lower than that in the control group ,the difference was statistically significant(P<0 .05);there was no statistically significant difference in ApoA1 ,ApoB ,ApoE and Lp(a)between the two groups (P>0 .05);the severity of pregnancy induced hypertension was positively correlated with the levels of TG ,LDL-C and TC ,and negatively correlated with HDL-C level .Conclusion The blood lipid level and BMI during middle stage of pregnancy in the preg-nant women with gestational hypertension are significantly higher than those in the normal pregnant women ,and the Lp(a)level has no statistically significant difference compared with normal pregnant women .Detecting the blood lipid level during the middle stage of pregnancy can early predict the occurrence and severity of pregnancy induced hypertension .lipid level can be used to predict the incidence and severity of pregnancy induced hypertension in pregnant women .关键词
妊娠高血压/妊娠中期/血脂/血脂蛋白Key words
hypertension of pregnancy/second trimester of pregnancy/blood lipid/lipoprotein引用本文复制引用
陈刘红,孔丽丽..妊娠高血压孕妇妊娠中期的血脂及血脂蛋白研究[J].检验医学与临床,2017,14(22):3316-3317,3320,3.基金项目
江苏省张家港市科技支撑计划资助项目(ZKS1320). （ZKS1320）
