四川医学2017，Vol.38Issue(9)：1004-1006,3.DOI:10.16252/j.cnki.issn1004-0501-2017.09.007
血糖水平对脑18F-FDG PET/CT显像影响研究
Effects of Blood Glucose Levels on Brain18F-FDG PET/CT Imaging
摘要
Abstract
Objective To investigate the effect of blood glucose concentration on 18F-FDG uptaking in brain PET/CTscans.Methods 70 patients who underwent whole-body and head PET/CT imaging in our hospital during January 2014 to December 2015 were retrospectively analyzed.Blood glucose of all patients was determined before scanning,and patients were divided into control group,slightly high blood glucose group and high blood glucose group.Visual analysis and semi quantitative analysis were adopted to analyze PET images and maximum standard uptake values were calculated according to cerebellar cortex as reference area.Results Blood glucose gradually increased following the sequence of control group,slightly high blood glucose group and high blood glucose group,the difference being statistically significant (F =200.369,P ＜ 0.05) and in the meantime,SUVmax of cerebellar cortex gradually decreased,the difference being statistically significant (F =14.207,P ＜ 0.05).Comparing high blood glucose group with control group or slightly high blood glucose group,the difference was statistically significant (P ＜ 0.05),but comparing slightly high blood glucose group with control group,the difference was not statistically significant(P ＞ 0.05).The brain uptake of 18F-FDG was negatively correlated to blood glucose concentration.Conclusion High blood glucose interferes with brain uptake of 18F-FDG and influences PET/CT imaging,so blood glucose concentration should be controlled within a reasonable range before PET/CT examination.关键词
血糖水平/脑显像/PET/CT/18F-FDGKey words
blood glucose level/brain imaging/PET/CT/18F-FDG分类
医药卫生引用本文复制引用
王治国,战莹,武晓丹,陆国秀,吴锐先,张宗鹏,张国旭..血糖水平对脑18F-FDG PET/CT显像影响研究[J].四川医学,2017,38(9):1004-1006,3.基金项目
辽宁省自然科学基金(编号:20140220066) （编号:20140220066）
辽宁省自然科学基金(编号:20170540927) （编号:20170540927）
