四川医学2017，Vol.38Issue(9)：1055-1058,4.DOI:10.16252/j.cnki.issn1004-0501-2017.09.022
无创正压通气治疗脓毒症所致急性呼吸窘迫综合征的疗效观察
Therapeutic Effect of Noninvasive Positive Pressure Ventilation on Acute Respiratory Distress Syndrome Induced by Sepsis
刘晓姝 1解郑良 1陈丽娟 1张静 1滕鸿1
作者信息
- 1. 四川省医学科学院·四川省人民医院呼吸内科,四川成都610072
- 折叠
摘要
Abstract
Objective To observe the clinical efficacy of noninvasive positive pressure ventilation(NPPV) in the treatment of sepsis-induced acute respiratory distress syndrome (ARDS)and to explore the factors that affect its efficacy.Methods We collected and analyzed the clinical data of 82 patients receiving NPPV in ICU with ARDS caused by sepsis from January 1,2012 to December 31,2016 and screened the relevant factors.Results The sequential organ falure assessment (SOFA) score serum C-reactive protein(CRP) and procalcitonin(PCT) were significantly lower in the NPPV successful group than those in the failed group,and the platelet(Plt) count was higher than that of the failure group.The difference was statistically significant(P ＜0.05).The difference of whether the oxygenation index(PaO2/FiO2)of the two groups was greater than 150mmHg and whether invasive positive pressure ventilation (IPPV)was used in the two groups was statistically significant(P ＜ 0.05);SOFA score ＜ 10 points,oxygenation index ≥150mmHg and Plt≥50 × 109/L were influence factors of NPPV efficacy.Conclusion NPPV has a certain value in treatment of sepsis caused by ARDS,and the success rate is higher when the patient's SOFA score ＜ 10 points,oxygenation index ≥150mmHg and Plt≥50 × 109/L.关键词
无创正压通气/脓毒症/急性呼吸窘迫综合征/保护性因素Key words
noninvasive positive pressure ventilation/sepsis/acute respiratory distress syndrome/protective factor分类
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刘晓姝,解郑良,陈丽娟,张静,滕鸿..无创正压通气治疗脓毒症所致急性呼吸窘迫综合征的疗效观察[J].四川医学,2017,38(9):1055-1058,4.
