世界中医药2017，Vol.12Issue(9)：2009-2013,5.DOI:10.3969/j.issn.1673-7202.2017.09.006
浅谈冠心病痰瘀互结证及内质网自噬在冠心病痰瘀互结证中的研究意义
Discussion on Significance of Coronary Heart Disease with Phlegm and Blood Stasis Pattern and Endoplasmic Reticulum Autophagy's Influence During its Process
摘要
Abstract
Phlegm turbidity and blood stasis are main pathogenesis basis for coronary heart disease (CHD),and play a key role in the whole process of CHD.This article firstly discussed CHD with phlegm and blood stasis pattern from its etiology,pathogenesis,treatment and biological basis.Among the biological basis,apoptosis influences the outcome and prognosis of CHD and endoplasmic reticulum autophagy (ER-phagy) is the key point to regulate apoptosis.Therefore this article investigated its role in the CHD with phlegm and blood stasis pattern from apoptosis.关键词
痰瘀互结证/冠心病/内质网自噬/细胞凋亡Key words
Phlegm and blood stasis pattern/Coronary heart disease/Endoplasmic reticulum autophagy/Apoptosis分类
医药卫生引用本文复制引用
王琛,胡镜清..浅谈冠心病痰瘀互结证及内质网自噬在冠心病痰瘀互结证中的研究意义[J].世界中医药,2017,12(9):2009-2013,5.基金项目
国家重点基础研究发展计划(973计划)项目(2014CB542903)——“基于冠心病痰瘀互结证辨证方法的创新研究” （973计划）
国家重大新药创制科技重大专项课(2013ZX09303301)——“中药新药临床研究技术平台规范建设” （2013ZX09303301）
中国中医科学院中医基础理论研究所基本科研业务费自主选题项目(YZ-1678) （YZ-1678）
