世界中医药2017，Vol.12Issue(9)：2084-2087,2092,5.DOI:10.3969/j.issn.1673-7202.2017.09.025
从cTnI探讨强心方对慢性心力衰竭患者心肌保护作用
Discussion on the Protective Effect of Qiangxin Fang on Myocardiumof Patients with Chronic Heart Failure from cTnI
摘要
Abstract
Objective:To observe the effect of Qiangxin Fang on levels of cardiac troponin I(cTnI) and N-terminal pro-brain natriuretic peptide (NT-proBNP) in the treatment to patient with chronic heart failure,and also to explore the protective effect of Qiangxin Fang on myocardial injury based on the changes of cTnI level.Methods:A total of 120 patients with chronic heart failure who were treated in outpatient and hospitalized in Shanghai Municipal Hospital of Traditional Chinese Medicine Affiliated to Shanghai University of Traditional Chinese Medicine from March 2016 to March 2017,were randomly divided into treatment group and control group,with 60 cases in each.The treatment group was treated with Qiangxin Fang combined with conventional western medicine treatment methods,while the control group was not received conventional western medicine treatment.Both groups were treated for 8 weeks.Results:After treatment,the levels of cTnI and NT-proBNP in two groups were significantly decreased (P ＜ 0.05).And the levels of cTnl and NT-proBNP in treatment group were significantly decreased compared with control group (P ＜ 0.05).Conclusion:Qiangxin Fang combined with conventional westem medicine treatment has improvement effect on levels of cTnI and NT-proBNP for patients with chronic heart failure,and Qiangxin Fang has protective effect on myocardial injury of patients with chronic heart failure.关键词
强心方/慢性心力衰竭/心肌肌钙蛋白I/N末端脑钠肽前体Key words
Qiangxin Fang/Chronic heart failure/Cardiac troponin I/N-terminal pro-brain natriuretic peptide分类
医药卫生引用本文复制引用
凌望,张蕾,程大雁,朱锦星,周苗,董耀荣,吴美平..从cTnI探讨强心方对慢性心力衰竭患者心肌保护作用[J].世界中医药,2017,12(9):2084-2087,2092,5.基金项目
国家自然科学基金项目(81473379,81673915) （81473379,81673915）
上海市自然科学基金项目(16ZR1434500) （16ZR1434500）
