生命科学研究2017，Vol.21Issue(5)：466-470,5.DOI:10.16605/j.cnki.1007-7847.2017.05.017
蜕膜自然杀伤细胞在正常妊娠中作用的研究进展
Progresses on the Role of Decidual NK Cells in Successful Pregnancy
摘要
Abstract
Decidual natural killer (dNK) cells accumulate in the maternal decidua during pregnancy and are directly in close contact with fetal trophoblasts.However,the mechanisms of dNK cells affecting pregnancy are still unknown.By secreting cytokines/chemokines and angiogenic factors,dNK cells participate in normal placentation with feto-matenal tolerance,spiral artery remodeling and neovascularization during decidualization in a successful pregnancy.Here,the researches about the effect of dNK cells on the development of pregnancy are reviewed.关键词
自然杀伤细胞/蜕膜/正常妊娠/螺旋动脉重铸/血管形成Key words
natural killer cell/deciduas/successful pregnancy/spiral artery remodeling/neovascularization分类
医药卫生引用本文复制引用
廖娥,邵勇..蜕膜自然杀伤细胞在正常妊娠中作用的研究进展[J].生命科学研究,2017,21(5):466-470,5.基金项目
国家自然科学基金资助项目(81471473) （81471473）
重庆市卫计委医学高端后备人才培养项目(2015XMSB0001298) （2015XMSB0001298）
