中国医疗设备2017，Vol.32Issue(11)：15-17,27,4.DOI:10.3969/j.issn.1674-1633.2017.11.005
双能量CT碘图评估肝硬化血流灌注的可行性分析
Feasibility Analysis of Dual Energy CT Iodine Maps in Assessing Blood Perfusion of Cirrhosis
摘要
Abstract
Objective To evaluate the feasibility of quantitative method for second-generation dual-source dual-energy CT (DECT) iodine maps in assessing changes in hepatic perfusion in patients with liver cirrhosis.Methods According to the Child-Pugh grading for liver functionality, 30 volunteers with normal liver functionality as well as 30 patients with liver cirrhosis were enrolled in this study, respectively. The hepatic arterial phase (Ia), intravenous iodine value (Ip) (AIF=Ia/Ip) and the difference of iodine concentration in portal vein (PVIC= IP-Ia) were measured and compared between the two groups.Results There was no significant difference in Ia, Ip, AIF and PVIC between liver cirrhosis group and normal group as well as right lobe (P>0.05). Statistical significant difference of parameters in odine maps were found between the two groups (P<0.05). There was no significant difference in CT values between the group with normal liver functionality and the group with liver cirrhotic in arterial phase (P>0.05), but significant difference was found in CT values in venous phase between the two groups (P<0.05).Conclusion The second-generation DECT iodine images can reflect the changes of liver perfusion in patients with liver cirrhosis and further provide a new method for quantitative assessment of patients with liver cirrhosis.关键词
肝硬化/双能量成像/双源CT/碘图/血流灌注Key words
liver cirrhosis/dual energy imaging/dual-source CT/iodine maps/hepatic perfusion分类
医药卫生引用本文复制引用
唐永强,石磊,李剑,石明国..双能量CT碘图评估肝硬化血流灌注的可行性分析[J].中国医疗设备,2017,32(11):15-17,27,4.基金项目
国家自然科学基金(81000648). （81000648）
