中国医疗设备2017，Vol.32Issue(11)：82-85,4.DOI:10.3969/j.issn.1674-1633.2017.11.020
探究实时剪切波弹性成像技术预测静脉
血栓硬度与溶栓疗效的相关性
Correlation of Venous Thrombosis and Thrombolytic Effects on Hardness of Real-Time Shear Wave Elastography Technology
夏晴 1孙顺吉 2马桂凤 3张嫚嫚 1林秀梅1
作者信息
- 1. 潍坊医学院医学影像系,山东潍坊 261000
- 2. 潍坊医学院附属医院 血管介入科,山东潍坊 261000
- 3. 潍坊医学院附属医院超声科,山东潍坊 261000
- 折叠
摘要
Abstract
Objective To quantitatively evaluate the hardness of deep venous thrombosis of lower extremity by using the shear wave elastography (SWE) technique, and to identify the relationship between the thrombolytic effect and thrombus hardness by different thrombolytic regimens (such as catheter directed thrombolysis, systemic thrombolysis) and the young's modulus pathways.Methods A total of 97 cases with symptoms of acute central complete venous thrombosis and definite venous thrombosis diagnosed by regular ultrasound, were included in this study. Patients were divided into cathetering thrombolysis group and systematic thrombolysis group. After 7-10 days of anticoagulation or thrombolytic therapy, patients in the two groups were further divided into cure group, effective group and ineffective group according to the different treatment result. The total cure rate and Young's modulus value were compared between the two groups. Besides, the patient's work characteristic curve was established to determine the effective critical value of the young's modulus. Results The Young's modulus in cure group, significant effective group and ineffective group in the two groups were significantly different (P<0.01), while that between the cure group and effective group of Young's modulus was not significant (P>0.05). The sensitivity and specificity of Young's modulus at 8.50 kPa was 92% and 93.7% respectively. The difference of the young's modulus between the cathetering thrombolysis group and systematic thrombolysis group was statistically significant (P<0.01).Conclusion The young's modulus of the real time SWE can quantitatively evaluate the thrombus hardness, and the hardness of thrombus is related to the thrombolytic effect. Therefore, the young modulus can predict the thrombolysis effect. According to the young's modulus of dissolved thrombus, the effect of thrombolytic therapy is better than that of systemic thrombolysis.关键词
实时剪切波弹性成像/杨氏模量/静脉血栓硬度/溶栓治疗Key words
real time shear wave elastography/Young's modulus/venous thrombosis hardness/thrombolytic therapy分类
医药卫生引用本文复制引用
夏晴,孙顺吉,马桂凤,张嫚嫚,林秀梅..探究实时剪切波弹性成像技术预测静脉
血栓硬度与溶栓疗效的相关性[J].中国医疗设备,2017,32(11):82-85,4.
