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芪苈强心胶囊对老年慢性心力衰竭患者心功能、血浆脑钠肽、D-二聚体及肌钙蛋白Ⅰ的影响

张金龙 谭亚萍 赵晓蓉 张冬梅

疑难病杂志2017,Vol.16Issue(11):1145-1148,4.
疑难病杂志2017,Vol.16Issue(11):1145-1148,4.DOI:10.3969/j.issn.1671-6450.2017.11.017

芪苈强心胶囊对老年慢性心力衰竭患者心功能、血浆脑钠肽、D-二聚体及肌钙蛋白Ⅰ的影响

The effect of Qiliqiangxin capsule on serum BNP,D-Dimer and cTnⅠ in patients with chronic heart

张金龙 1谭亚萍 1赵晓蓉 1张冬梅1

作者信息

  • 1. 621000 四川省绵阳市中医医院内6科
  • 折叠

摘要

Abstract

Objective To investigate the effect of Qiliqiangxin capsule on serum BNP and D-Dimer,cTnⅠ of patients with chronic heart failure.Methods Eighty-four patients with chronic heart failure according to the random number table method were divided into control group and observation group.Observation group had 42 patients,in the conventional manner plus Qiliqiangxin capsule treatment;control group of 42 patients were treated in a conventional manner.Analyzing of two groups of patients before and after treatment,the levels of plasma BNP,D-Dimer,cTnⅠ,6 minute walk distance and cardiac ultrasound indicators and related clinical total efficiency.Results The efficiency of observation group (92.86%) was significantly higher than control group (66.67%),the different was statistically significant (x2 =11.648,P < 0.05).Compared with that before treatment,the 6 min walk distance SV,LVEDD and LVEF were improved in both groups,and the observation group was superior to control group(t =4.461,2.387,3.706,4.482,P < 0.01).Two groups of patients ' plasma BNP and D-Dimer,cTnⅠ levels were decreased compared to before treatment,but the observation group was better than the control group with statistically significant different (t =6.108,5.891,7.102,P < 0.05);Conclusion It proved that the Qiliqiangxin capsule could effectively improve patients' heart function,enable the plasma BNP and D-Dimer,cTnⅠ levels significantly reduced,which helped to treat chronic heart failure,worthy of promotion and application in clinical practice.

关键词

心力衰竭,慢性/芪苈强心胶囊/老年/脑钠肽/肌钙蛋白Ⅰ/D-二聚体

Key words

Heart failure, chronic/Qiliqiangxin capsule/Aged/Brain natriuretic peptide/cTnⅠ/D-Dimer

引用本文复制引用

张金龙,谭亚萍,赵晓蓉,张冬梅..芪苈强心胶囊对老年慢性心力衰竭患者心功能、血浆脑钠肽、D-二聚体及肌钙蛋白Ⅰ的影响[J].疑难病杂志,2017,16(11):1145-1148,4.

疑难病杂志

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1671-6450

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