摘要
Abstract
Objective To analyze the clinical features of young and middle-aged patients with acute ST-segment elevation myocardial infarction(STEMI).Methods This retrospective study was conducted in Department of Cardiology,Beijing Tiantan Hospital,Capital Medical University.The enrolled participants were totaled 183 cases who were diagnosed as acute STEMI in 2016,including patients who had acute STEMI occurring within 12 h,and those who had acute STEMI occurring within 24 h but met the indications for emergency revascularization and underwent emergency percutaneous coronary intervention (PCI).We reviewed their baseline data,coronary angiographic parameters,laboratory results,cardiac function and structural parameters,and the incidence of major adverse cardiovascular events within 30 days after operation.Results The participants were divided intothe young and middle-aged group (95 cases aged ＜ 60) and elderly group (88 cases aged ≥60) based on age.The two groups had significant differences in sex distribution,visiting time after the onset of acute STEMI,history of diabetes,family history of premature coronary heart disease,smoking index and BMI (all P ＜ 0.05).Compared with the elderly group,the young and middle-aged group was found with higher ratio of treatment with tirofiban administered intravenousfy,larger total dose of tirofiban administered,lower ratio of treatment with IABP,higher levels of serum TG,TC,LDL-C,high-sensitive cardiac troponin Ⅰ (hs-cTnl),creatine kinase isoenzyme (CK-MB) and BNP,and lower levels of serum creatinine and Killip class (all P ＜ 0.05).The incidence of major adverse cardiovascular events and that of malignant arrhythmia occurring within 30 days after the surgery was lower in the young and middle-aged group (P ＜ 0.05).Conclusion Compared with the elderly group,the young and middle-aged group can visit more timely after the onset of acute STEMI,and they have milder lesions assessed by coronary angiography,higher success rate of vascular recanalization and better prognosis,so they should be actively involved in the interventional therapy for improving the prognosis.关键词
心肌梗死/冠状血管造影术/血管成形术,气囊,冠状动脉Key words
Myocardial infarction/Coronary angiography/Angioplasty,balloon,coronary分类
医药卫生
