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谷氨酸和肽聚糖在促进细菌间纳米管形成中作用的研究

钟桥石 杭亚平 刘衍伶 丁慧 俞凤 陈艳慧 胡龙华

中国人兽共患病学报2017,Vol.33Issue(10):893-896,4.
中国人兽共患病学报2017,Vol.33Issue(10):893-896,4.DOI:10.3969/j.issn.1002-2694.2017.10.008

谷氨酸和肽聚糖在促进细菌间纳米管形成中作用的研究

The role of glutamate and peptidoglycan in nanotubes formation between adjacent bacteria

钟桥石 1杭亚平 1刘衍伶 2丁慧 1俞凤 1陈艳慧 1胡龙华1

作者信息

  • 1. 南昌大学第二附属医院检验科,南昌 330006
  • 2. 南昌大学第一附属医院检验科,南昌 330006
  • 折叠

摘要

Abstract

We investigated the formation mechanism and immediate constituents of nanotubes between adjacent bacteria,pre venting rapid increase of drug-resistant bacteria provide potential targets.We used scanning electron microscopy(SEM) to observe formation of nanotubes;glutamic was determined by surface desorption atmospheric pressure chemical ionization mass spectrometry(SDAPCI-MS)and peptidoglycan was determined by enzyme linked immunosorbent assay(ELISA) in the forma tion of nanotubes before and after.The results showed that Staphylococcus aureus and Escherichia coli consumed more glutamic after formation of nanotubes;at the same time,the concentration of peptidoglycan in nanotubes formation of S.aureus and E.coli increased significantly.This study illuminated the glutamic and peptidoglycanin role mechanism of nanotubes form.We found that peptidoglycan is constituents of nanotubes and glutamic is the main energy source for the formation of nanotubes.

关键词

纳米管/谷氨酸/肽聚糖

Key words

nanotubes/glutamic/peptidoglycan

引用本文复制引用

钟桥石,杭亚平,刘衍伶,丁慧,俞凤,陈艳慧,胡龙华..谷氨酸和肽聚糖在促进细菌间纳米管形成中作用的研究[J].中国人兽共患病学报,2017,33(10):893-896,4.

基金项目

Funded by the Youth Natural Science Foundation of Jiangxi and the Natural Science Foundation of Jiangxi (No.20133BAB205062).江西省青年自然基金资助项目(No.20171BAB2150798)和江西省自然基金资助项目(No.20133BAB205062)联合资助 (No.20133BAB205062)

中国人兽共患病学报

OA北大核心CSCDCSTPCD

1002-2694

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