中国人兽共患病学报2017，Vol.33Issue(10)：923-926,4.DOI:10.3969/j.issn.1002-2694.2017.10.015
结核分枝杆菌吡嗪酰胺耐药相关基因研究进展
Research progress of association between gene mutation and pyrazinamide resistance in Mycobacterium tuberculosis
摘要
Abstract
Pyrazinamide (PZA) is an important anti-tuberculosis drug especially for treating multidrug-resistant tuberculo sis (MDR-TB).In recent years,the incidence of Mycobacterium tuberculosis' resistance to pyrazinamide has increased.At present,the mechanism of drug resistance has not been clearly elucidated.In this review,the association between gene mutation and pyrazinamide resistance in Mycobacterium tuberculosis will be summarized.关键词
结核分枝杆菌/吡嗪酰胺/基因变异/耐药机制Key words
Mycobacterium tuberculosis/pyrazinamide/gene mutation/drug resistance mechanism分类
医药卫生引用本文复制引用
曹志敏,陈玲..结核分枝杆菌吡嗪酰胺耐药相关基因研究进展[J].中国人兽共患病学报,2017,33(10):923-926,4.基金项目
Supported by the National Natural Science Foundation of China(No.81360002).国家自然科学基金(No.81360002)资助 （No.81360002）
