中国现代医学杂志2017，Vol.27Issue(27)：64-70,7.DOI:10.3969/j.issn.1005-8982.2017.27.012
尿毒症患者冠状动脉钙化与血压变异性的相关性研究
Association between blood pressure variability and vascular calcification in uremic patients
摘要
Abstract
Objective To investigate the association between vascular calcification and blood pressure variability (BPV) in uremic patients. Methods Medical history and laboratory values of the uremic patients were collected. Pulse pressure (PP), blood pressure variability and circadian rhythm of each patient were recorded by ambulatory blood pressure monitoring (ABPM). Coronary artery calcification score (CACS) of each patient was calculated by plain scan dual-resource spiral CT, and correlation between CACS and BPV was analyzed. Results In 72 uremic patients who received coronary CT scan and ABPM, coronary calcification positive group presented significantly higher 24 hPP, dPP, nPP, nCVS and nCVD ( < 0.05) compared with coronary calcification negative group. Moderate calcification group presented significantly higher 24 hPP, dPP and nPP ( <0.05) compared with coronary calcification negative group. The CACS was significant positive correlated with 24 h CVSBP ( =0.468, =0.028), nCVSBP ( =0.641, = 0.001), 24 h CVS ( =0.540, =0.009) and nCVS ( =0.756, =0.000) respectively. Conclusions Coronary calcification positive group presents higher PP and night blood pressure variability coefficient over negative group. CACS and systolic pressure variability coefficient are positively correlated.关键词
血压变异性/血管钙化/尿毒症Key words
uremia/blood pressure variability/vascular calcification分类
医药卫生引用本文复制引用
胡闪闪,杨宁,孙喜霞,李平,王大鹏,于长青..尿毒症患者冠状动脉钙化与血压变异性的相关性研究[J].中国现代医学杂志,2017,27(27):64-70,7.基金项目
大连市优秀青年科技人才基金(No:2008J23JH036) （No:2008J23JH036）
