中国医院用药评价与分析2017，Vol.17Issue(8)：1061-1062,2.DOI:10.14009/j.issn.1672-2124.2017.08.021
紫杉醇联合奥沙利铂治疗晚期与复发性宫颈癌的疗效观察
Observation on Efficacy of Paclitaxel Combined with Oxaliplatin in Treatment of Advanced and Recurrent Cervical Cancer
陈福春 1钟莉2
作者信息
- 1. 福建医科大学附属龙岩第一医院妇科,福建龙岩364000
- 2. 龙岩市第二医院肿瘤科,福建龙岩364000
- 折叠
摘要
Abstract
OBJECTIVE:To probe into the efficacy and safety of paclitaxel combined with oxaliplatin in treatment of advanced and recurrent cervical cancer.METHODS:90 patients with advanced and recurrent cervical cancer admitted into Longyan the First Hospital Affiliated to Fujian Medical University from Feb.2011 to Mar.2012 were selected to be divided into observation group and control group via the random number table,with 45 cases in each.The control group was treated with paclitaxel combined with cisplatin,while the observation group received paclitaxel combined with oxaliplatin.The clinical efficacy,5-year survival and incidence of adverse drug reactions of two groups were observed.RESULTS:The total effective rate of observation group and control group were respectively 95.56％ (43/45) and 93.33 (42/45),yet the 5-year survival rate were respectively 88.89％ (40/45) and 86.67％ (39/45),without any statistical significance between two groups (P ＞ 0.05).The incidence of adverse drug reactions of observation group was 4.44％ (2/45),significantly lower than that of control group 20.00％ (9/45),with statistically significant difference (P ＜ 0.05).CONCLUSIONS:The efficacy of paclitaxel combined with oxaliplatin in treatment of advanced and recurrent cervical cancer is significant with few adverse drug reactions and high safety.关键词
紫杉醇/奥沙利铂/晚期与复发性宫颈癌/效果/安全性Key words
Paclitaxel/Oxaliplatin/Advanced and recurrent cervical cancer/Effects/Safety分类
医药卫生引用本文复制引用
陈福春,钟莉..紫杉醇联合奥沙利铂治疗晚期与复发性宫颈癌的疗效观察[J].中国医院用药评价与分析,2017,17(8):1061-1062,2.
