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香薷传统切制与产地加工炮制一体化比较研究

孙冬月 王晓婷 王馨雅 高慧

中国中医药信息杂志2017,Vol.24Issue(12):72-76,5.
中国中医药信息杂志2017,Vol.24Issue(12):72-76,5.DOI:10.3969/j.issn.1005-5304.2017.12.018

香薷传统切制与产地加工炮制一体化比较研究

Comparative Study on Traditional Cutting Processing and Integration Processing of Origin of Moslae Herba

孙冬月 1王晓婷 1王馨雅 1高慧1

作者信息

  • 1. 辽宁中医药大学药学院,辽宁 大连 116600
  • 折叠

摘要

Abstract

Objective To provide the feasible basis for the implementation of integration processing technology of origin of Moslae Herba by comparing the traditional cutting processing and integration processing of origin of Moslae Herba. Methods Taking the softening time, the length of cutting section and the drying temperature as the investigation factors of the traditional cutting processing, and the cutting length, drying temperature and drying time as the investigation factors of the integration processing of origin, L9(34) orthogonal test was used. Carvacrol, thymol, volatile oil content were setting as the evaluation indexes, the traditional cutting processing and the integration processing of origin were optimized, and the two selected process were compared. The contents of carvacrol and thymol were deterrmined by Agilent 1200 high performance liquid chromatography and ECOSIL-C18 column. The mobile phase was acetonitrile-0.2% acetic acid, gradient elution, with wavelength of 274 nm, flow rate of 1.0 mL/min, sample volume of 20 μL. The extraction of the volatile oil was in accordance with the volatile oil determination method in Chinese Pharmacopoeia 2015 edition. Results The optimized traditional cutting processing: softening 1 h with 3 times amount of water, cutting to 1.0 cm, drying at 50–60 ℃. The optimized integration processing of origin: cutting to 1.0 cm in fresh, drying at 50–60 ℃, drying to 36 h. The contents of carvacrol, thymol, and volatile oil in the optimum integration processing of origin were all higher than the traditional cutting processing. Conclusion The technology of integration processing of origin is simple and convenient, which can make up the defects of the complicated traditional cutting processing and the lessen of effective components, and is feasible.

关键词

香薷/产地加工炮制一体化/香荆芥酚/麝香草酚/挥发油

Key words

Moslae Herba/integration processing of origin/carvacrol/thymol/volatile oil

分类

医药卫生

引用本文复制引用

孙冬月,王晓婷,王馨雅,高慧..香薷传统切制与产地加工炮制一体化比较研究[J].中国中医药信息杂志,2017,24(12):72-76,5.

基金项目

中医药行业科研专项(201507002-06) (201507002-06)

中国中医药信息杂志

OACSCDCSTPCD

1005-5304

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