中国中医药信息杂志2017,Vol.24Issue(12):114-116,3.DOI:10.3969/j.issn.1005-5304.2017.12.029
论脾虚是乙肝病毒相关性肾炎的关键机转
Discussion on Spleen Deficiency as the Key Mechanism of Hepatitis B Virus Associated Glomerulonephritis
摘要
Abstract
This article tried to discuss that spleen deficiency is the key mechanism of hepatitis B virus associated glomerulonephritis from TCM and Western medicine viewpoint. From the view of pathophysiology, energy metabolic disorder caused by mitochondrial injury and its series of damages are similar to symptoms caused by spleen deficiency appeared as yin fire and organs dystrophy, so mitochondrial injure belongs to spleen deficiency. And mitochondrial damage can further aggravate the virus replication of hepatitis B virus associated glomerulonephritis, causing damage to the kidney. Therefore, from the view of Western medicine, it can be known that spleen deficiency determines whether the liver function damage in the process of hepatitis B virus associated glomerulonephritis and lower energizer transformation. In terms of TCM, spleen deficiency plays an important role in all stages of the disease, and determines the outcome and prognosis of the disease. Therefore, this article proposed that the spleen deficiency is the mechanism of hepatitis B virus associated glomerulonephritis, which can provide references for clinic.关键词
脾虚/线粒体损伤/乙肝病毒相关性肾炎/机制Key words
spleen deficiency/mitochondrial injury/hepatitis B virus associated glomerulonephritis/mechanism分类
医药卫生引用本文复制引用
许勇镇,阮诗玮,丘余良..论脾虚是乙肝病毒相关性肾炎的关键机转[J].中国中医药信息杂志,2017,24(12):114-116,3.基金项目
国家中医临床研究基地业务建设科研专项课题(JDZX2012017) (JDZX2012017)
福建省中医药科研项目(wzsb201305、wzsb201312) (wzsb201305、wzsb201312)