北华大学学报（自然科学版）2017，Vol.18Issue(6)：747-750,4.DOI:10.11713/j.issn.1009-4822.2017.06.010
人骨肉瘤发生的分子基础和潜在治疗靶点
Molecular Pathogenesis Basis of Human Osteosarcoma and Potential Targets for Therapy
摘要
Abstract
Osteosarcoma,with high migration and poor prognosis,is one of the most common primary malignant bone tumors. For the disease mechanism of molecular biology level studies have advanced,the cause can be divided into three directions:osteogenesis differentiation defect,abnormal expression of oncogenes and tumor suppressor genes,and abnormal signal path. This paper briefly describes the gene,protein,cell factor, inflammatory cytokines,receptors and so on with abnormal activities related to the occurrence and development of osteosarcoma,which can be the potential therapeutic target.关键词
骨肉瘤/肿瘤治疗/癌基因Key words
osteosarcoma/tumor therapy/oncogenes分类
医药卫生引用本文复制引用
王丹,张涵瑜,刘亮..人骨肉瘤发生的分子基础和潜在治疗靶点[J].北华大学学报（自然科学版）,2017,18(6):747-750,4.基金项目
吉林省卫生厅基金项目(20152056). （20152056）
