北华大学学报（自然科学版）2017，Vol.18Issue(6)：751-754,4.DOI:10.11713/j.issn.1009-4822.2017.06.011
浅表性骨肉瘤病理分析及其微血管密度
Clinicopathological and Microvascular Density on the Surface Osteosarcoma
摘要
Abstract
Objective To explore the clinicopathological features of surface osteosarcoma and its microvascular density. Method 13 cases of surface osteosarcoma patients confirmed by surgery pathology were selected,the clinical and pathological data were retrospectively analyzed,using immunohistochemical SP method to detect patients with CD105 and the expression of CD105-MVD,and comparing 13 cases with benign bone tumor contrast. Results Symptom can appear in patients with knee flexion activities is limited,different degree of pain and swelling,tenderness,tardy increase lump,skin temperature increased and so on. Patients with imaging examination can clearly display the tumor size,position,edge and its relationship with the surrounding soft tissue and bone cortex infringement case;CD105 positive expression rate of surface osteosarcoma and CD105-MVD were significantly higher than benign bone tumors,contrast differences statistically significant (P < 0. 05 ). Conclusion Surface osteosarcoma diagnosis relies mainly on the clinical,imaging and pathological aspects,a comprehensive diagnosis of superficial CD105-MVD increased obviously in osteosarcoma,CD105-MVD may be involved in the formation of tumor blood vessels,which affects the occurrence,development and prognosis of surface osteosarcoma.关键词
浅表性骨肉瘤/临床/病理/微血管密度Key words
osteosarcoma/clinical/pathology/microvascular density分类
医药卫生引用本文复制引用
郭建平,王法佳,白长双,刘权祥..浅表性骨肉瘤病理分析及其微血管密度[J].北华大学学报（自然科学版）,2017,18(6):751-754,4.基金项目
吉林省教育厅科学技术研究项目(JJKH20170052KJ). （JJKH20170052KJ）
