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内镜黏膜下剥离术与切除术治疗胃食管病变疗效分析

何元清 何子彬 付雄 王学培 胡兵

北华大学学报(自然科学版)2017,Vol.18Issue(6):762-765,4.
北华大学学报(自然科学版)2017,Vol.18Issue(6):762-765,4.DOI:10.11713/j.issn.1009-4822.2017.06.014

内镜黏膜下剥离术与切除术治疗胃食管病变疗效分析

On Clinical Effect of Endoscopy Mucosal Resection and Endoscopic Submucosal Dissection in Gastroesophageal Mucoscal Lesions

何元清 1何子彬 1付雄 1王学培 1胡兵2

作者信息

  • 1. 广元市第三人民医院,四川广元 628001
  • 2. 四川大学华西医院,四川成都 610041
  • 折叠

摘要

Abstract

Objective To comparatively study the clinical effect of EMR and ESD in gastroesophageal lesions. Method 77 patients who met the including criteria were selected. All the patients were divided into twogroups,EMR group (45 cases)and ESD group (32 cases)according to their operation methods. The operation time,en bloc resection rate,complications and recurrence rate between the two groups were compared. Results The en bloc resection rate (90 . 6%),R0 resection rate (78 . 1%),the lateral margin negative rate (87 . 5%)and vertical cut negative rate (84 . 4%)in ESD group were significantly higher than those in EMR group (41 . 7%,44 . 4%,53 . 3%,75 . 6%,respectively )(P<0 . 05 ). The average operation time in ESD group (56 . 8 ± 21 . 4 )min was significantly higher than that in EMR group (30 . 2 ± 12 . 5 )min (P<0 . 05 ). The recurrence rate of ESD group (6 . 3%)was significantly lower than that in EMR group (45 . 0%)(P<0 . 05 ). The occurred esophageal stricture after the operation (3 . 1%)(P<0 . 05 ) in patients in ESD group was significantly lower than that (6. 3%)in EMR group,and the perforation rate of ESD group was significantly higher than that in EMR group (P<0 . 05 ). There is no obvious difference in hemorrhage between two group (P>0. 05). Conclusion Compared with EMR,ESD could remove the mucoscal lesions at one time with high efficiency,lower recurrence rate and less complications,which could result in a better clinical effect.

关键词

胃食管病变/内镜黏膜下剥离术/内镜黏膜切除术

Key words

gastroesophageal mucoscal lesions/endoscopic submucosal dissection/endoscopy mucosal resection

分类

医药卫生

引用本文复制引用

何元清,何子彬,付雄,王学培,胡兵..内镜黏膜下剥离术与切除术治疗胃食管病变疗效分析[J].北华大学学报(自然科学版),2017,18(6):762-765,4.

基金项目

四川省科技厅资助项目(2012JY0063). (2012JY0063)

北华大学学报(自然科学版)

OACSTPCD

1009-4822

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